- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT146 描述 Anti-Occludin Antibody Alternate Names - Occludin
背景信息 Occludin is a 65-kDa integral plasma-membrane protein located at the tight junctions. It is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Occludin is believed to prevent the transport of macromolecules through the tight junction. Encoded by the OLCN gene, occludin spans the plasma membrane four times, forming two extracellular loops and exposing its NH2 and COOH terminus to the cytosol. This cytoplasmic tail binds directly to the ZO family of proteins, which link the protein complex to the actin cytoskeleton. Phosphorylation/dephosphorylation plays a major role in regulation of occludin and tight junctions. Expression of occludin is required for infection of liver cells by hepatitis C virus (HCV). 产品信息 格式 Affinity Purified 控制 - Human kidney tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-Occludin Antibody is validated for use in Western Blotting for the detection of Occludin. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the N-terminus of human Occludin. 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the N-terminus of Occludin. 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. Predicted to react with Porcine, Primate, Equine, Canine, Bovine, Mouse, and Rat based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_002529
基因符号 - OCLN
纯化方法 Affinity purified UniProt编号 - Q16625
产品使用声明 质量保证 Evaluated by Western Blot in human kidney tissue lysate.
Western Blot Analysis: 0.2 µg/mL of this antibody detected Occludin in 10 µg of human kidney tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,0500-1790,Guava EasyCyte Mini Service Total 2 Year Plan
下一件merck millipore产品：merck millipore,默克密理博,FCMAB117P,Anti-SSEA-1 Antibody, clone MC-480, PE conjugate
相关产品
merck millipore,默克密理博,05-1214,Anti-FXR2 Antibody, clone 2C8.2
merck millipore,默克密理博,MAB3502-I,Anti-Angiotensin Converting Enzyme Antibody, clone 2E2
merck millipore,默克密理博,MAB345A4,Anti-O4 Antibody, clone 81, Alexa Fluor488 Conjugate
merck millipore,默克密理博,LSK2ABA60,Montage 离心柱与 PROSEP-A 介质
merck millipore,默克密理博,0500-1790,Guava EasyCyte Mini Service Total 2 Year Plan
merck millipore,默克密理博,FCMAB117P,Anti-SSEA-1 Antibody, clone MC-480, PE conjugate
merck millipore,默克密理博,AB15067,Anti-EMX1 Antibody
merck millipore,默克密理博,AB5158-50UL,Anti-Calcium Channel Antibody, Voltage Gated α 1D
merck millipore,默克密理博,MAB3418,Anti-MAP2 Antibody, clone AP20
