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经验配方 CAS号 C₉H₁₂N₂O₅ 3690-10-6 描述 概述 A cell-permeable chemically stable cytidine analog that displays antitumor properties. Acts as transition state analog inhibitor of cytidine deaminase by binding at the active site as covalent hydrates. Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo. 产品目录编号 691400 品牌系列 Calbiochem®
同义词 1-(β-D-Ribofuranosyl)-1,2-dihydropyrimidin-2-one, 2-Pyrimidone-1-β-D-riboside 参考 参考 Cheng, J.C., et al. 2004. Cancer Cell 6, 151.
Cheng, J.C., et al. 2003. J. Natl. Cancer Inst. 95, 399.
Zhou, L., et al. 2002. J. Mol. Biol. 321, 591.
Barchi, J.J., Jr., et al. 1992. J. Org. Chem. 57, 536.
Frick, L., et al. 1989. Biochemistry 28, 9423.产品信息 CAS号 3690-10-6 具有ATP竞争性 N 形式 Off-white solid Hill配方 C₉H₁₂N₂O₅ 化学配方 C₉H₁₂N₂O₅ Molar Mass 228.2 可逆 N 结构配方图像 生物信息 主靶 Cytidine deaminase 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO or MeOH 储存和货运信息 货运代码 Blue Ice Only
毒性 Standard Handling
储存 +2°C to +8°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
From Catalog:
Desc. Field- added "cell-permeable包装信息 惰性气体下包装 Packaged under inert gas
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