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描述 概述 Full-length, recombinant, human UbcH5c expressed in E. coli. UbcH5c, an E2 ubiquitin ligase, is highly homologous to the yeast UbC4/5 family of E2 enzymes. UbcH5c, together with UbcH5a and UbcH5b, are the most active class of E2 enzymes in cell extracts and are associated with regulation of transcription factors such as p53, NF-κB3, and c-Fos. The active enzyme is useful in the study of ubiquitin regulation and inhibitor screening. 产品目录编号 662098 品牌系列 Calbiochem®
同义词 UBD2D3, Ubiquitin-conjugating enzyme E2 D3 参考 参考 Brzovic, P.S., et al. 2006. Cell Cycle 5, 2867.
Gehrke, S.G., et al. 2003 Blood. 101, 3288.
Nuber, U., And Scheffner, M., 1999. J. Biol. Chem. 274, 7576.
Schwarz, S.E., et al. 1998. J. Biol. Chem. 273, 12148.
Jensen, J., et al. 1995. J. Biol. Chem. 270, 30408.
Scheffner, M., et al. 1994. Proc. Natl. Acad. Sci. 91, 8797.
产品信息 配方 In 50 mM HEPES, 50 mM NaCl, 1 mM DTT, 10% glycerol, pH 7.0. Molar Mass 17000 生物信息 纯度 ≥95% by SDS-PAGE 浓缩标签 Please refer to vial label for lot-specific concentration
储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C).
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