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merck millipore,默克密理博,356790,Glyphosine - CAS 2439-99-8 - Calbiochem
产品名称：Glyphosine - CAS 2439-99-8 - Calbiochem
产品型号：356790
A plant growth regulator that also enhances anti-B:9-23 TCR-dependent T cell activation by modulating murine class II MHC I-Ag7-mediated B:9-23 presentation on APCs.
merck millipore,默克密理博,356790,Glyphosine - CAS 2439-99-8 - Calbiochem
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重要规格表
经验配方 CAS号 C₄H₁₁NO₈P₂ 2439-99-8 描述 概述 A glycine-phosphonic acid compound, negatively charged at neutral pH, with immunomodulatory and anti-diabetic properties. Shown to enhance CD4+ T cell response to B-chain of insulin (amino acids 9-23) even at 10 nM levels (EC50 = 70.6 nM). Occupies a pocket 9 of I-Ag7 (the class II molecules of the diabetes-prone NOD mice) and alters TCR/peptide-MHC affinity. Stimulates IL-10 secretion in splenocyes in non-obese diabetic (NOD) mice. Daily administration of glyphosine is shown to delay the onset of diabetes in NOD mice. Acts as a competitive inhibitor of phoshoenolpyruvate carboxylase in plants. 产品目录编号 356790 品牌系列 Calbiochem®
同义词 N,N-bis(Phosphonomethyl)glycine, 2-(bis(Phosphonomethyl)amino)acetic acid, Cp41845, Polaris 参考 参考 Michels, A.W., et al. 2011. J. Immunol. 187, 5921.
Stadinski, B.D., et al. 2010. Proc. Natl. Acad. Sci. USA 107, 10978.
Podesta, F.E., et al. 1987. Plant Cell Physiol. 28, 375.产品信息 CAS号 2439-99-8 形式 White solid Hill配方 C₄H₁₁NO₈P₂ 化学配方 C₄H₁₁NO₈P₂ Molar Mass 263.1 吸湿 Hygroscopic
结构配方图像 生物信息 纯度 ≥98% by NMR 理化信息 溶解度 H₂O 安全信息 R相 R: 41
Risk of serious damage to eyes.S相 S: 26
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Corrosive
有害材料注意事项： Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存 +2°C to +8°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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