• merck millipore,默克密理博,654271,MetAP2 Inhibitor, A832234 - Calbiochem
  • merck millipore,默克密理博,654271,MetAP2 Inhibitor, A832234 - Calbiochem

    产品名称:MetAP2 Inhibitor, A832234 - Calbiochem
    产品型号:654271
    The MetAP2 Inhibitor, A832234 controls the biological activity of MetAP2.

    merck millipore,默克密理博,654271,MetAP2 Inhibitor, A832234 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,654271,MetAP2 Inhibitor, A832234 - Calbiochem

    重要规格表

    经验配方
    C₂₄H₂₉FN₂O₄S
    描述
    概述 A cell-permeable anthranilic acid sulfonamide compound that acts as a potent and reversible inhibitor of methionine aminopetidase-2 (MetAP2, IC50 = 11 nM). Acts by directly targeting the active site of MetAP2 without any significant binding to human serum albumin. Also shown to inhibit cellular MetAP2 activity (EC50 = 5.3 nM) and block the proliferation of HT1080 fibrosarcoma cells (EC50 = 6 nM).
    产品目录编号 654271
    品牌系列 Calbiochem®
    同义词 Methionine aminopeptidase-2 Inhibitor, 2-[({2-[(1Z)-3-(Diethylamino)-1-propenyl]-4-fluorophenyl}-sulfonyl)amino]-5,6,7,8-tetrahydro-1-naphthalenecarboxylic Acid, Methionyl aminopeptidase 2 Inhibitor
    参考
    参考 Sheppard, G. S., et al. 2006. J Med Chem. 49, 3832
    产品信息
    形式 Light beige solid
    Hill配方 C₂₄H₂₉FN₂O₄S
    Molar Mass 460.56
    可逆 Y
    结构配方图像
    生物信息
    主靶 MetAP2
    主靶IC50 11 nM
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,654271,MetAP2 Inhibitor, A832234 - Calbiochem

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