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描述 概述 Recombinant, human TRAIL (amino acids 114-281) expressed in E. coli. Ligand for TRAIL receptors DR4 and DR5. Displays potent antitumor activity against selected targets and induces apoptosis in a number of transformed cell lines, but not in normal tissues. 产品目录编号 616374 品牌系列 Calbiochem®
同义词 Apo2L, Human, Recombinant, E. coli, TNF-Related Apoptosis-Inducing Ligand, Human, Recombinant, E. coli 参考 参考 Lin, Y., et al. 2000. Mol. Cell. Biol. 20, 6638.
Mitsaides, N., et al. 2000. Cancer Res. 60, 4122.
Griffith, T.S., et al. 1999. J. Exp. Med. 189, 1343.
Mariani, S.M., et al. 1997. J. Cell Biol. 137, 221.
Pan, G., et al. 1997. Science 276, 111.
Pan, G., et al. 1997. Science 277, 815.
Sheridan, J.P., et al. 1997. Science 277, 818.
Pitti, R.M., et al. 1996. J. Biol. Chem. 271, 12687.
Wiley, S.R., et al. 1995. Immunity 3, 673.产品信息 形式 Liquid 配方 In 500 mM NaCl, 10 mM Na₂HPO₄, 2.7 mM KCl, 2 mM KH₂PO₄, 0.1 mM DTT, ≤10% glycerol. Molar Mass 18000 生物信息 生物活性 Induces apoptosis in U937 cells at 1 μg/ml within 5 h. 纯度 ≥95% by SDS-PAGE 浓缩标签 Please refer to vial label for lot-specific concentration
理化信息 污染物 endotoxin <0.1 EU/µg TRAIL 储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze
(-70°C).
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