merck millipore,默克密理愽
  • merck millipore,默克密理博,581011,Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem

  • merck millipore,默克密理博,581011,Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem

    产品名称：Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem
    产品型号：581011
    The Telomerase Inhibitor IX, also referenced under CAS 368449-04-1, controls the biological activity of Telomerase. This small molecule/inhibitor is primarily used for Cell Structure applications.

    merck millipore,默克密理博,581011,Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,581011,Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₀H₁₆N₂O₆368449-04-1
    描述
    概述 A cell-permeable, bis-catechol containing, m-phenylenediamide compound that displays anti-proliferative properties. Acts as a potent, reversible inhibitor of telomerase activity (IC50 = 670 nM, TRAP lysate prepared from U937 cells). Prolonged treatment with MST-312 has been reported to result in telomere shortening and growth arrest in U937 cells. Does not inhibit the activity of Taq DNA polymerase (IC50 >3 µM).
    产品目录编号 581011
    品牌系列 Calbiochem®
    同义词 MST-312, N,Nʹ-bis(2,3-Dihydroxybenzoyl)-1,3-phenylenediamine
    参考
    参考 Seimiya, H., et al. 2005. Cancer Cell 7, 25.
    Seimiya, H., et al. 2002. Mol. Cancer Ther. 1, 657.
    产品信息
    CAS号 368449-04-1
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₀H₁₆N₂O₆
    化学配方 C₂₀H₁₆N₂O₆
    Molar Mass 380.4
    可逆 Y
    结构配方图像
    生物信息
    主靶 TRAP lysate prepared from U937 cells
    主靶IC50 670 nM against telomerase activity in TRAP lysate prepared from U937 cells
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,581011,Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem

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