• merck millipore,默克密理博,573127,STAT3 Inhibitor XII, SPI - Calbiochem
  • merck millipore,默克密理博,573127,STAT3 Inhibitor XII, SPI - Calbiochem

    产品名称:STAT3 Inhibitor XII, SPI - Calbiochem
    产品型号:573127
    The STAT3 Inhibitor XII, SPI controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,573127,STAT3 Inhibitor XII, SPI - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,573127,STAT3 Inhibitor XII, SPI - Calbiochem

    重要规格表

    经验配方
    C₁₄₆H₂₃₈N₄₀O₄₂
    描述
    概述 A cell-permeable STAT3 SH2 domain-derived (588-615) 28-mer peptide that competitively prevents STAT3 binding to cognate pTyr peptide motif, represses STAT3 dimerization, induces apoptosis and acts as a selective constitutive STAT3 activation inhibitor in several tumor cells at 50 µM. Shown to localize in nucleus, potently block STAT3 phosphorylation, DNA-binding and transcriptional activities with minimal effect on STAT1, STAT5 and MEK signaling.
    产品目录编号 573127
    品牌系列 Calbiochem®
    同义词 H₂N-FISKERERAILSTKPPGTFLLRFSESSK-CO₂H
    参考
    参考 Zhao, W., et al. 2010. J. Biol. Chem. 285, 35855.
    产品信息
    形式 White solid
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₁₄₆H₂₃₈N₄₀O₄₂
    化学配方 C₁₄₆H₂₃₈N₄₀O₄₂
    Molar Mass 3225.7
    吸湿 Hygroscopic
    肽序列 H-Phe-Ile-Ser-Lys-Glu-Arg-Glu-Arg-Ala-Ile-Leu-Ser-Tyr-Lys-Pro-Pro-Gly-Tyr-Phe-Leu-Leu-Arg-Phe-Ser-Glu-Ser-Ser-Lys-OH
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO or H₂O
    肽序列 H-Phe-Ile-Ser-Lys-Glu-Arg-Glu-Arg-Ala-Ile-Leu-Ser-Tyr-Lys-Pro-Pro-Gly-Tyr-Phe-Leu-Leu-Arg-Phe-Ser-Glu-Ser-Ser-Lys-OH
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,573127,STAT3 Inhibitor XII, SPI - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,MABF512,Anti-CD11b Antibody (human/mouse), APC-Cy7, clone M1/70
下一件merck millipore产品:merck millipore,默克密理博,374813,Hemocyanin, Keyhole Limpet, Megathura crenulata, High Purity, Endotoxin-Free, Glycerol



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