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merck millipore,默克密理博,573127,STAT3 Inhibitor XII, SPI - Calbiochem
产品名称:STAT3 Inhibitor XII, SPI - Calbiochem
产品型号:573127
The STAT3 Inhibitor XII, SPI controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
merck millipore,默克密理博,573127,STAT3 Inhibitor XII, SPI - Calbiochem
- 产品介绍
重要规格表
经验配方 C₁₄₆H₂₃₈N₄₀O₄₂ 描述 概述 A cell-permeable STAT3 SH2 domain-derived (588-615) 28-mer peptide that competitively prevents STAT3 binding to cognate pTyr peptide motif, represses STAT3 dimerization, induces apoptosis and acts as a selective constitutive STAT3 activation inhibitor in several tumor cells at 50 µM. Shown to localize in nucleus, potently block STAT3 phosphorylation, DNA-binding and transcriptional activities with minimal effect on STAT1, STAT5 and MEK signaling. 产品目录编号 573127 品牌系列 Calbiochem®
同义词 H₂N-FISKERERAILSTKPPGTFLLRFSESSK-CO₂H 参考 参考 Zhao, W., et al. 2010. J. Biol. Chem. 285, 35855. 产品信息 形式 White solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₁₄₆H₂₃₈N₄₀O₄₂ 化学配方 C₁₄₆H₂₃₈N₄₀O₄₂ Molar Mass 3225.7 吸湿 Hygroscopic
肽序列 H-Phe-Ile-Ser-Lys-Glu-Arg-Glu-Arg-Ala-Ile-Leu-Ser-Tyr-Lys-Pro-Pro-Gly-Tyr-Phe-Leu-Leu-Arg-Phe-Ser-Glu-Ser-Ser-Lys-OH 生物信息 纯度 ≥95% by HPLC 理化信息 溶解度 DMSO or H₂O 肽序列 H-Phe-Ile-Ser-Lys-Glu-Arg-Glu-Arg-Ala-Ile-Leu-Ser-Tyr-Lys-Pro-Pro-Gly-Tyr-Phe-Leu-Leu-Arg-Phe-Ser-Glu-Ser-Ser-Lys-OH 储存和货运信息 货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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