merck millipore,默克密理愽
  • merck millipore,默克密理博,567022,InSolution™ Simvastatin, Sodium Salt - Calbiochem

  • merck millipore,默克密理博,567022,InSolution™ Simvastatin, Sodium Salt - Calbiochem

    产品名称：InSolution™ Simvastatin, Sodium Salt - Calbiochem
    产品型号：567022
    Carboxylate form of Simvastatin that is active in whole cells and in cell-free assays.

    merck millipore,默克密理博,567022,InSolution™ Simvastatin, Sodium Salt - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,567022,InSolution™ Simvastatin, Sodium Salt - Calbiochem

    重要规格表

    经验配方
    C₂₅H₃₉O₆ •Na
    描述
    概述 Carboxylate form of Simvastatin (Cat. No. 567020) that is active in whole cells and in cell-free assays. A lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation. Also inhibits glucose-induced Ca2+-signaling and insulin secretion by blocking L-type Ca2+ channels in rat islet β-cells. Inhibits cell proliferation of human smooth muscle cells. The solid form of this compound (Cat. No. 567021) is also available.
    产品目录编号 567022
    品牌系列 Calbiochem®
    同义词 L-Type Calcium Channel Blocker VI
    参考
    参考 Yada, T., et al. 1999. Br. J. Pharmacol. 126, 1205.
    Clutterbuck, R.D., et al. 1998. Br. J. Haematol. 102, 522.
    Yokoyama, K., et al. 1998. Mol. Biochem. Parasitol. 94, 87.
    Negre-Aminou, P., et al. 1997. Biochim. Biophys. Acta 1345, 259.
    Vrtovsnik, F., et al. 1997. Kidney Int. 52, 1016.
    Keyomarsi, K., et al. 1991. Cancer Res. 51, 3602.
    产品信息
    形式 Liquid
    配方 A 10 mM (5 mg/1.09 ml) solution of Simvastatin, Sodium Salt (Cat. No. 567021) in H₂O.
    Hill配方 C₂₅H₃₉O₆ •Na
    化学配方 C₂₅H₃₉O₆ •Na
    Molar Mass 458.6
    可逆 Y
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    安全信息
    R相 R: 36/38

    Irritating to eyes and skin.
    S相 S: 26

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Irritant
    储存 ≤ -70°C
    避光 Protect from light
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C).
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,567022,InSolution™ Simvastatin, Sodium Salt - Calbiochem

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