merck millipore,默克密理愽
  • merck millipore,默克密理博,565749,β-Secretase Inhibitor II - CAS 263563-09-3 - Calbiochem

  • merck millipore,默克密理博,565749,β-Secretase Inhibitor II - CAS 263563-09-3 - Calbiochem

    产品名称：β-Secretase Inhibitor II - CAS 263563-09-3 - Calbiochem
    产品型号：565749
    The β-Secretase Inhibitor II, also referenced under CAS 263563-09-3, controls the biological activity of β-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.

    merck millipore,默克密理博,565749,β-Secretase Inhibitor II - CAS 263563-09-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,565749,β-Secretase Inhibitor II - CAS 263563-09-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₅H₃₉N₃O₅263563-09-3
    描述
    概述 A potent, cell-permeable, and reversible inhibitor of β-secretase. Corresponds to the β-secretase cleavage site (VNL-DA) of the Swedish mutant Amyloid Precursor Protein (APP). Inhibits the formation of both Aβtotal (IC50 = 700 nM) and Aβ1-42 (IC50 = 2.5 µM) in Chinese hamster ovary (CHO) cells stable transfected with wild-type APP751.
    产品目录编号 565749
    品牌系列 Calbiochem®
    同义词 Z-VLL-CHO, N-Benzyloxycarbonyl-Val-Leu-leucinal
    参考
    参考 Abbenante, G., et al. 2000. Biochem. Biophys. Res. Commun. 268, 133.
    产品信息
    CAS号 263563-09-3
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₅H₃₉N₃O₅
    化学配方 C₂₅H₃₉N₃O₅
    Molar Mass 461.6
    肽序列 Z-Val-Leu-Leu-CHO
    可逆 Y
    结构配方图像
    生物信息
    主靶 β-secretase
    主靶IC50 700 nM and 2.5 µM against Aβtotal and Aβ1-42, respectively
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    肽序列 Z-Val-Leu-Leu-CHO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,565749,β-Secretase Inhibitor II - CAS 263563-09-3 - Calbiochem

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