- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H ICC, WB Rb Serum Polyclonal Antibody 描述 产品目录编号 07-612 品牌系列 Upstate
商名 - Upstate
描述 Anti-Peroxiredoxin 4 Antibody 产品信息 格式 Serum 演示 antiserum with 0.05% sodium azide before the addition of glycerol to 30% 应用 应用 Anti-Peroxiredoxin 4 Antibody detects level of Peroxiredoxin 4 & has been published & validated for use in WB & IC. 主要应用 - Immunocytochemistry
- Western Blotting
生物信息 免疫原品种 Full-length human Peroxiredoxin 4 recombinant protein tagged with hexahistidine 宿主 Rabbit 特异性 Peroxiredoxin 4 同种型 IgG 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_006406
Entrez基因汇总 The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. 基因符号 - AOE37-2
- PRDX4
- Peroxiredoxin-4
- AOE372
- Prx-IV
纯化方法 Serum UniProt编号 - Q13162
UniProt汇总 FUNCTION: SwissProt: Q13162 # Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
SIZE: 271 amino acids; 30540 Da
SUBUNIT: Homodimer or heterodimer with PRDX1; disulfide-linked, upon oxidation (By similarity).
SUBCELLULAR LOCATION: Cytoplasm.
SIMILARITY: SwissProt: Q13162 ## Belongs to the ahpC/TSA family.
MISCELLANEOUS: The active site is the redox-active Cys-124 oxidized to Cys-SOH. Cys-SOH rapidly reacts with Cys-245-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin. & Irreversibly inactivated by overoxidation of Cys- 124 (to Cys-SO(3)H) upon oxidative stress.产品使用声明 质量保证 routinely evaluated by immunoblot on RIPA lysates from Du145 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 50 µL
上一件merck millipore产品：merck millipore,默克密理博,MABS62,Anti-GREB1 Antibody, clone GREB1Ab
下一件merck millipore产品：merck millipore,默克密理博,MABT129,Anti-VE-Cadherin Antibody (CD144), clone BV9
相关产品
merck millipore,默克密理博,MAB1678,Anti-Filamin A Antibody, clone PM6/317
merck millipore,默克密理博,AB3738,Anti-β Lactamase Antibody
merck millipore,默克密理博,71975,KOD Xtreme™ Hot Start DNA Polymerase
merck millipore,默克密理博,SCR019,Neural Stem Cell Marker Characterization Kit
merck millipore,默克密理博,MABS62,Anti-GREB1 Antibody, clone GREB1Ab
merck millipore,默克密理博,MABT129,Anti-VE-Cadherin Antibody (CD144), clone BV9
merck millipore,默克密理博,SF-901,Vimentin; Human, Cyanine 3, RNA Detection Probe,SmartFlare
merck millipore,默克密理博,101543,精胺酸盐酸盐
merck millipore,默克密理博,565749,β-Secretase Inhibitor II - CAS 263563-09-3 - Calbiochem
merck millipore,默克密理博,FCMAB112F,Anti-SOX-2 Antibody, clone 6G1.2, FITC conjugate