merck millipore,默克密理博,553506,RAP, Human, Recombinant, E. coli

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Merck Millipore 默克密理愽

merck millipore,默克密理博,553506,RAP, Human, Recombinant, E. coli
产品名称：RAP, Human, Recombinant, E. coli
产品型号：553506

merck millipore,默克密理博,553506,RAP, Human, Recombinant, E. coli

描述
概述	Recombinant, human RAP fused to GST, expressed in E. coli, and subsequently cleaved with thrombin to remove GST. Antagonizes the ligand binding of certain members of the low-density lipoprotein receptor family such as low density lipoprotein receptor-related protein (LRP) and very low-density lipoprotein (VLDL) receptor. Promotes the proper folding and subsequent exocytic trafficking of the wild-type low density lipoprotein receptor (LDLR) and several of its class 2 mutants. Expressed as a GST-fusion protein that is subsequently cleaved with thrombin. Typical concentrations to block LRP or VLDL receptor are 200-300 nM. For antagonism of LDLR, 1 µM is recommended.
产品目录编号	553506
品牌系列	Calbiochem®
同义词	Receptor Associated Protein

参考
参考	Li, Y., et al. 2002. Biochemistry 41, 4921. Salicioni, A.M., et al. 2002. J. Biol. Chem. 277, 16160. Anderson, O.M., et al. 2001. Biochemistry 40, 15408. Bu, G. 2001. Int. Rev. Cytol. 209, 79. Williams, S.E., et al. 1992. J. Biol. Chem. 267, 9035

生物信息
纯度	≥90% by SDS-PAGE
浓缩标签	Please refer to vial label for lot-specific concentration

储存和货运信息
货运代码	Dry Ice Only
毒性	Standard Handling
储存	≤ -70°C
避免冻结 / 解冻	Avoid freeze/thaw
无需冷冻	No
特殊指南	Following initial thaw, aliquot and freeze (-70°C).

merck millipore,默克密理博,553506,RAP, Human, Recombinant, E. coli

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