merck millipore,默克密理博,371209,Dkk-2, Mouse, Recombinant

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merck millipore,默克密理博,371209,Dkk-2, Mouse, Recombinant
产品名称：Dkk-2, Mouse, Recombinant
产品型号：371209

merck millipore,默克密理博,371209,Dkk-2, Mouse, Recombinant

产品介绍

merck millipore,默克密理博,371209,Dkk-2, Mouse, Recombinant

重要规格表

纯度
≥95% by SDS-PAGE

描述
概述	Recombinant, mouse Dickkopf related protein 2 (Dkk-2) consisting of amino acids 26-259 and expressed in S. frugiperda 21 cells with a C-terminal His•Tag^® sequence. Dkk proteins are expressed in mesenchymal tissues and control epithelial transformations.
产品目录编号	371209
品牌系列	Calbiochem®

参考
参考	Morvan, F. et al. 2006. J. Bone Miner. Res. 21, 934. Mukhopadhyay, M. et al. 2006. Development 133, 2149. Niehrs, C. 2006. Oncogene 25, 7469. Li, X. et al. 2005. Nat. Genet. 37, 945. Bullock, C.M. et al. 2004. Mol. Pharmacol. 65, 582. Mao, B. and C. Niehrs 2003. Gene 302, 179. Brott, B. and S.Y. Sokol 2002. Mol. Cell. Biol. 22, 6100. Li, L. et al. 2002. J. Biol. Chem. 277, 5977. Mao, B. et al. 2002. Nature 417, 664. Mao, B. et al. 2001. Nature 411, 321. Wu, W. et al. 2000. Current Biol. 10,1611. Monaghan, A.P. et al. 1999. Mech. Dev. 87, 45. Krupnik, V.E. et al. 1999. Gene 238, 301.

参考

Morvan, F. et al. 2006. J. Bone Miner. Res. 21, 934.
Mukhopadhyay, M. et al. 2006. Development 133, 2149.
Niehrs, C. 2006. Oncogene 25, 7469.
Li, X. et al. 2005. Nat. Genet. 37, 945.
Bullock, C.M. et al. 2004. Mol. Pharmacol. 65, 582.
Mao, B. and C. Niehrs 2003. Gene 302, 179.
Brott, B. and S.Y. Sokol 2002. Mol. Cell. Biol. 22, 6100.
Li, L. et al. 2002. J. Biol. Chem. 277, 5977.
Mao, B. et al. 2002. Nature 417, 664.
Mao, B. et al. 2001. Nature 411, 321.
Wu, W. et al. 2000. Current Biol. 10,1611.
Monaghan, A.P. et al. 1999. Mech. Dev. 87, 45.
Krupnik, V.E. et al. 1999. Gene 238, 301.

产品信息
形式	Solid
配方	Lyophilized from 0.2 µm filtered PBS, BSA.

生物信息
生物活性	Inhibition assay: Inhibits WNT-3a-induced alkaline phosphatase production in MC3T3-E1 mouse osteoblastic cells in the presence of BMP-2. Competetive Binding Assay: Inhibits 50% binding of biotinylated rhDkk-1 (200 ng/ml) to immobilized rmKremen (4 µg/ml) at a concentration of 5-15 µg/ml.
纯度	≥95% by SDS-PAGE

理化信息
污染物	Endotoxin: <1.0 EU per/µg protein

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	-20°C
无需冷冻	No
特殊指南	Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.