merck millipore,默克密理愽
  • merck millipore,默克密理博,401486,IKK Inhibitor VII - CAS 873225-46-8 - Calbiochem

  • merck millipore,默克密理博,401486,IKK Inhibitor VII - CAS 873225-46-8 - Calbiochem

    产品名称：IKK Inhibitor VII - CAS 873225-46-8 - Calbiochem
    产品型号：401486
    The IKK Inhibitor VII, also referenced under CAS 873225-46-8, controls the biological activity of IKK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicati More>>

    merck millipore,默克密理博,401486,IKK Inhibitor VII - CAS 873225-46-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,401486,IKK Inhibitor VII - CAS 873225-46-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₈H₂₉N₅OS873225-46-8
    描述
    概述 A cell-permeable benzamido-pyrimidine compound that acts as a potent, selective, and ATP-competitive inhibitor of IKK (IC50 = 40 nM, 70 nM, and 200 nM for IKK-2, IKK complex, and IKK-1, respectively). Inhibits cellular IκBα degradation and NF-κB-mediated gene expression in vitro in HUVEC cells and has been shown to exhibit excellent in vivo efficacy both in mice and rats. Also available as a 10 mM solution in DMSO (Cat. No. 505378).
    产品目录编号 401486
    品牌系列 Calbiochem®
    同义词 IKK 16
    参考
    参考 Waelchli, R., et al. 2006. Bioorg. Med. Chem. Lett. 16, 108.
    产品信息
    CAS号 873225-46-8
    具有ATP竞争性 Y
    形式 Pale yellow solid
    Hill配方 C₂₈H₂₉N₅OS
    化学配方 C₂₈H₂₉N₅OS
    Molar Mass 483.6
    可逆 N
    结构配方图像
    生物信息
    主靶 IKK
    主靶IC50 40 nM, 70 nM, and 200 nM for IKK-2, IKK complex, and IKK-1, respectively
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    安全信息
    R相 R: 22

    Harmful if swallowed.
    S相 S: 22-24/25

    Do not breathe dust.
    Avoid contact with skin and eyes.
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Harmful
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,401486,IKK Inhibitor VII - CAS 873225-46-8 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,07-396,Anti-Raf-1 Antibody


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