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描述 概述 Recombinant, human RAD51 fused at the N-terminus to a His•Tag® sequence and expressed in E. coli. The human RAD51 is a mammalian homologue of yeast RAD51 and bacterial RecA and plays a pivotal role in the homologous recombination pathway for DNA double-strand break (DSB) repair. RAD51 has been shown to colocalize with tumor suppressor proteins BRCA1 (Cat. No. 203659) and BRCA2 in DNA-damage-induced foci and RAD51 is known to interact directly with BRCA2. 产品目录编号 553504 品牌系列 Calbiochem®
参考 参考 West, S.C. 2003. Nat. Rev. Mol. Cell Biol. 4, 435.
Jasin, M. 2002. Oncogene 21, 8981.
Symington, L.S., et al. 2002. Microbiol. Mol. Biol. Rev. 66, 630.
Daboussi, F., et al. 2002. Cell. Signal. 14, 969.
Liu, Y. and West, S.C. 2002. Breast Cancer Res. 4, 9.产品信息 形式 Liquid 配方 In 100 mM KCl, 20 mM Tris-HCl, 1 mM DTT, 0.2 mM EDTA, 20% glycerol, pH 8.0. Molar Mass 38000 生物信息 纯度 ≥95% by SDS-PAGE 浓缩标签 Please refer to vial label for lot-specific concentration
储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C).
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