merck millipore,默克密理愽
  • merck millipore,默克密理博,539741,PTP1B Inhibitor - CAS 765317-72-4 - Calbiochem

  • merck millipore,默克密理博,539741,PTP1B Inhibitor - CAS 765317-72-4 - Calbiochem

    产品名称：PTP1B Inhibitor - CAS 765317-72-4 - Calbiochem
    产品型号：539741
    The PTP1B Inhibitor, also referenced under CAS 765317-72-4, controls the biological activity of PTP1B. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicati More>>

    merck millipore,默克密理博,539741,PTP1B Inhibitor - CAS 765317-72-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,539741,PTP1B Inhibitor - CAS 765317-72-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₆H₁₉Br₂N₃O₇S₃765317-72-4
    描述
    概述 A cell-permeable sulfanamido-benzbromarone compound that acts as a selective, reversible and non-competitive allosteric inhibitor of PTP1B (IC50 = 4 µM and 8 µM for PTP1B403 and PTP1B298, respectively). Binds to a novel site away from the catalytic pocket and inhibits PTP1B activity by preventing closure of the WPD loop. Also available in InSolution™ format (Cat. No. 539749).
    产品目录编号 539741
    品牌系列 Calbiochem®
    同义词 3-(3,5-Dibromo-4-hydroxy-benzoyl)-2-ethyl-benzofuran-6-sulfonicacid-(4-(thiazol-2-ylsulfamyl)-phenyl)-amide, PTP Inhibitor XXII
    参考
    参考 Wiesmann, C., et al. 2004. Nat. Struct. Mol. Biol. 11, 730.
    产品信息
    CAS号 765317-72-4
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₆H₁₉Br₂N₃O₇S₃
    化学配方 C₂₆H₁₉Br₂N₃O₇S₃
    Molar Mass 741.5
    可逆 Y
    结构配方图像
    生物信息
    主靶 PTP1B403
    主靶IC50 4 µM and 8 µM for PTP1B403 and PTP1B298, respectively
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Blue Ice Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,539741,PTP1B Inhibitor - CAS 765317-72-4 - Calbiochem

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