merck millipore,默克密理愽
  • merck millipore,默克密理博,525189,Phospholipase C-γ-2, His•Tag, Human, Recombinant, S. frugiperda

  • merck millipore,默克密理博,525189,Phospholipase C-γ-2, His•Tag, Human, Recombinant, S. frugiperda

    产品名称：Phospholipase C-γ-2, His•Tag, Human, Recombinant, S. frugiperda
    产品型号：525189


    merck millipore,默克密理博,525189,Phospholipase C-γ-2, His•Tag, Human, Recombinant, S. frugiperda

  • 产品介绍
  • merck millipore,默克密理博,525189,Phospholipase C-γ-2, His•Tag, Human, Recombinant, S. frugiperda

    重要规格表
    描述
    概述 Full-length, recombinant, human phospholipase C γ-2 fused at the N-terminus to His•Tag® and S•Tag™ sequences and expressed in S. frugiperda insect cells. This preparation is qualified for use as a substrate for protein tyrosine kinases in in vitro assays. Intrinsic enzyme activity has not been tested. Production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes, which are crucial enzymes in transmembrane signaling. PLC-γ-2 is phosphorylated on tyrosine residues following ligand-induced activation of a variety of growth factor receptors and immune system receptors, resulting in increased phospholipase activity. The full-length proteins contains the following domains: C2 domain (aa 1059-1152); PH domain (aa 20-131); PI-PLC X-box catalytic domain (aa 312-456); PI-PLC Y-box catalytic domain (aa 930-1044); two SH2 domains (aa 532-635, aa 646-735); and a SH3 domain (aa 769-829). It has been reported to be phosphorylated at Tyr753 and Tyr759 (Btk, Src, Fyn, Lck), and Tyr1217 and Tyr1245 by Bcr-Abl.
    产品目录编号 525189
    品牌系列 Calbiochem®
    同义词 Phospholipase C-γ-2, Human, Recombinant
    应用数据
    参考
    参考 Rodriguez, R., et al. 2001. J. Biol. Chem. 276, 47982.
    Lennon, G., et al. 1996. Genomics 33, 151.
    产品信息
    形式 Liquid
    配方 In PBS.
    Molar Mass 153600
    生物信息
    纯度 ≥90% by SDS-PAGE
    浓缩标签 Please refer to vial label for lot-specific concentration
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Irritant
    储存 ≤ -70°C
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C).

    merck millipore,默克密理博,525189,Phospholipase C-γ-2, His•Tag, Human, Recombinant, S. frugiperda

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下一件merck millipore产品：merck millipore,默克密理博,07-1230,Anti-GADD45α Antibody


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