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merck millipore,默克密理博,07-1230,Anti-GADD45α Antibody
产品名称：Anti-GADD45α Antibody
产品型号：07-1230
Anti-GADD45α Antibody is a rabbit polyclonal antibody for detection of GADD45α also known as DNA-damage-inducible transcript, Growth arrest & DNA-damage-inducible protein GADD45 alpha & has been valid More>>
merck millipore,默克密理博,07-1230,Anti-GADD45α Antibody
- 产品介绍
Replacement Information Replacement Information 07-1230 is a recommended replacement for AB3863 重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H, R WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-1230 Replaces AB3863 品牌系列 Upstate
商名 - Upstate
描述 Anti-GADD45α Antibody Alternate Names - Growth arrest and DNA-damage-inducible, alpha
- DNA-damage-inducible transcript
- Growth arrest and DNA-damage-inducible protein GADD45 alpha
- Growth arrest and DNA-damage-inducible 45 alpha
- Growth arrest and DNA-damage-inducible
产品信息 格式 Purified 控制 - HEK293, Lung tissue, Kidney tissue
演示 Purified rabbit polyclonal IgG in buffer containing 0.02 M Phosphate with 0.15 M NaCl, pH 7.6 and 0.1% sodium azide as a preservative. 应用 应用 Anti-GADD45α Antibody is a rabbit polyclonal antibody for detection of GADD45α also known as DNA-damage-inducible transcript, Growth arrest & DNA-damage-inducible protein GADD45 alpha & has been validated in WB,IHC(P). 主要应用 - Western Blotting
应用说明 Immunohistochemistry(paraffin): Representative testing from a previous lot.
Optimal Staining of GADD45 Polyclonal Antibody: Placenta GADD45 staining on human placental lining cells, pretreated with citrate buffer, pH 6.0. A previous lot of this antibody was diluted to 1 µg/mL, using IHC-Select® detection with HRP-DAB. Immunoreactivity is seen as membrane staining.生物信息 免疫原品种 Synthetic peptide corresponding to the N-terminus of human GADD45α (MTLEEFSAGEQKTERMDKVGDALEE). 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes GADD45α, also known as Growth Arrest and DNA-Damage-inducible, alpha. 同种型 IgG 品种反应性 MouseHumanRat Species Reactivity Note Human, Rat and Mouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_001924
Entrez基因汇总 This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. [provided by RefSeq].
基因符号 - DDIT-1
- GADD45A
- DDIT1
- GADD45
纯化方法 Protein A purfied UniProt编号 - P24522
UniProt汇总 FUNCTION: Binds to proliferating cell nuclear antigen. Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
SUBUNIT: Interacts with GADD45GIP1.
INDUCTION: By UV radiation, X-rays, growth arrest and alkylating
agents. The induction is mediate by some kinase(s) other than PKC.
DISEASE: Induction of GADD45 in ataxia telangiectasia cells is abnormal.
SIMILARITY: Belongs to the GADD45 family.
产品使用声明 质量保证 Routinely evaluated by Western Blot on HEK293 lysates. Western Blot Analysis: 1:500 dilution of this lot detected GADD45A on 10 μg of HEK293 lysates. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable at 2-8 °C in undiluted aliquots for up to 6 months from date of receipt. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,AB9668,Anti-Tau phospho Threonine 231 Antibody
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