- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,525145,sPLA₂-IIA Inhibitor I - Calbiochem
产品名称：sPLA₂-IIA Inhibitor I - Calbiochem
产品型号：525145
The sPLA₂-IIA Inhibitor I controls the biological activity of sPLA₂-IIA. This small molecule/inhibitor is primarily used for Cell Signaling applications.
merck millipore,默克密理博,525145,sPLA₂-IIA Inhibitor I - Calbiochem
- 产品介绍
重要规格表
经验配方 C₄₁H₅₀N₈O₆ · CF₃CO₂H 描述 概述 A highly hydrophobic cyclic pentapeptide that selectively binds and acts as a potent inhibitor of sPLA2-IIA (human type IIA secreted phospholipase A2; IC50 = 12.8 μM). Shown to effectively block sPLA2-IIA-induced PGE2 production at 100 nM in human rheumatoid synoviocytes and is non-toxic at doses up to 10 μM. Does not have any significant effect on the activities of porcine sPLA2-IB, Naja naja sPLA2-IB, or Crotalus durissus sPLA2-IIA even at 10 μM concentration. 产品目录编号 525145 品牌系列 Calbiochem®
同义词 c(2NapA)LS(2NapA)R, TFA 参考 参考 Church, W.B., et al. 2001. J. Biol. Chem. 276, 33156. 产品信息 具有ATP竞争性 N 形式 White lyophilized solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₄₁H₅₀N₈O₆ · CF₃CO₂H 化学配方 C₄₁H₅₀N₈O₆ · CF₃CO₂H Molar Mass 864.9 吸湿 Hygroscopic
肽序列 cyclic(2-NaphthylAla-Leu-Ser-2-NaphthylAla-Arg)•TFA 可逆 N 生物信息 主靶 sPLA2-IIA (human type IIA secreted phospholipase A2 主靶IC50 12.8 µM against sPLA2-IIA (human type IIA secreted phospholipase A2 纯度 ≥95% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO 肽序列 cyclic(2-NaphthylAla-Leu-Ser-2-NaphthylAla-Arg)•TFA 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
上一件merck millipore产品：merck millipore,默克密理博,05-217,Anti-PI3 Kinase Antibody, p85, N-SH2,
下一件merck millipore产品：merck millipore,默克密理博,MAB1435,Anti-Macrophages/Monocytes Antibody, clone ED-1
merck millipore,默克密理博,239836,Cyclophilin A Inhibitor - CAS 1186372-20-2 - Calbiochem
merck millipore,默克密理博,ST1200,Anti-Ubiquitin Mouse mAb (FK2)
merck millipore,默克密理博,17-10246,ChIPAb+™ Histone H2A.Bbd - ChIP Validated Antibody and Primer Set
merck millipore,默克密理博,MABF916,Anti-CD8a (human) Antibody, AlexaFluor488, clone HIT8a
merck millipore,默克密理博,05-217,Anti-PI3 Kinase Antibody, p85, N-SH2,
merck millipore,默克密理博,MAB1435,Anti-Macrophages/Monocytes Antibody, clone ED-1
merck millipore,默克密理博,252000,DDMAB - CAS 15163-30-1 - Calbiochem
merck millipore,默克密理博,04-1062,Anti-GFAP (NT) Antibody, clone EPR1034Y, rabbit monoclonal
merck millipore,默克密理博,0500-1810,Guava EasyCyte Mini (SSC) Service Total 2 Year Plan
merck millipore,默克密理博,516557,Anti-PGC-1, C-Terminal (777-797) Rabbit pAb