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描述 概述 Full-length, recombinant, human phosphodiesterase 4B2 (accession no. L20971) fused at the N-terminus to a His•Tag® sequence and expressed in S. frugiperda using a baculovirus expression system. Plays a significant role in the regulation of inflammatory cell activation. PDE4B2 is a predominant isoform in neutrophils and monocytes. Supplied as a partially purified, catalytically active preparation. 产品目录编号 524736 品牌系列 Calbiochem®
同义词 PDE4B2, cAMP-Specific Phosphodiesterase 4B2 应用数据 
Phosphodiesterase 4B2 was treated with increasing concentrations of the inhibitor, rolipram, and the activity assayed. the IC50 for this inhibition is 1.77 µM.参考 参考 Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
Smith, P.G., et al. 2005 Blood 105, 308.
Baroja, M.L., et al. 1999. J. Immunol. 162, 2016.产品信息 活性 ≥ 0.25 units/µl 形式 Liquid 配方 In 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3. 储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C).
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