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merck millipore,默克密理博,516562,Pertussis Toxin, Salt-Free, Bordetella pertussis - CAS 70323-44-3 - Calbiochem
产品名称：Pertussis Toxin, Salt-Free, Bordetella pertussis - CAS 70323-44-3 - Calbiochem
产品型号：516562
A protein endotoxin that catalyzes ADP-ribosylation of guanine nucleotide-binding regulatory proteins.
merck millipore,默克密理博,516562,Pertussis Toxin, Salt-Free, Bordetella pertussis - CAS 70323-44-3 - Calbiochem
- 产品介绍
- merck millipore,默克密理博,516562,Pertussis Toxin, Salt-Free, Bordetella pertussis - CAS 70323-44-3 - Calbiochem
重要规格表
CAS号 70323-44-3 描述 概述 A protein endotoxin that catalyzes ADP-ribosylation of guanine nucleotide-binding regulatory proteins. The holotoxin has five dissimilar subunits S-1, S-2, S-3, S-4, and S-5, in a molar ratio of 1:1:1:2:1, S-1 (A protomer) is responsible for the enzymatic activity of the toxin, and S-2, S-3, S-4, and S-5 form the B oligomer which is responsible for the toxins binding to the cell surface. NOTE: This product is not activated, hence for use in cell-free systems, activation is required. 产品目录编号 516562 品牌系列 Calbiochem®
同义词 Islet-activating Protein 参考 参考 Fryer, M.W. 1992. Neurosci. Lett. 146, 84.
Gierschik, P. 1992. Curr. Topics Microbiol. Immunol. 175, 69.
Harada, J., et al. 1992. Eur. J. Pharmacol. 227, 301.
Hausman, S.Z., and Burns, D.L. 1992. J. Biol. Chem. 267, 13735.
Kaslow, H.R., and Burns, D.L. 1992. FASEB J. 6, 2684.
Zhu, J., et al. 1992. J. Pharmacol. Exp. Therap. 263, 1479.
Kaslow, H.R., et al. 1987. Biochemistry 26, 123.
Hewlett, E.L., et al. 1983. Infect. Immun. 40, 1198.
Moss, J., et al. 1983. J. Biol. Chem. 258, 11879.产品信息 CAS号 70323-44-3 具有ATP竞争性 N 形式 Salt-free lyophilized solid 可逆 N 生物信息 生物活性 ≤0.01 ng/ml. The activity is defined as the lowest concentration that promotes a clustering pattern in the CHO cell assay 主靶 ADP-ribosylation of guanine nucleotide-binding regulatory proteins 纯度 Five distinct bands by SDS-PAGE 理化信息 细胞可渗透 N 溶解度 Sterile dH₂O GHS安全信息 RTECS XW5883750 安全信息 R相 R: 23/24/25
Toxic by inhalation, in contact with skin and if swallowed.S相 S: 36/37/39-45
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).储存和货运信息 货运代码 Ambient Temperature Only
毒性 Toxic
有害材料注意事项： Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存 +2°C to +8°C
无需冷冻 Yes
特殊指南 Following reconstitution, store in the refrigerator (4°C). For long term storage in solution, reconstitute with a high ionic strength buffer, such as 100 mM sodium phosphate, 500 mM sodium chloride, pH 7.0. Stock solutions are stable for up to 6 months for use in CHO cell assays and for up to 2 months for use in non-cellular systems. 加拿大出口规定 Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
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