merck millipore,默克密理愽
  • merck millipore,默克密理博,495621,Olomoucine II - CAS 500735-47-7 - Calbiochem

  • merck millipore,默克密理博,495621,Olomoucine II - CAS 500735-47-7 - Calbiochem

    产品名称：Olomoucine II - CAS 500735-47-7 - Calbiochem
    产品型号：495621
    A cell-permeable 2,6,9-trisubstituted purine analog that acts as a potent, reversible, and ATP-competitive inhibitor of Cdk1/B.

    merck millipore,默克密理博,495621,Olomoucine II - CAS 500735-47-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,495621,Olomoucine II - CAS 500735-47-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₉H₂₆N₆O₂500735-47-7
    描述
    概述 A cell-permeable 2,6,9-trisubstituted purine analog that acts as a potent, reversible, and ATP-competitive inhibitor of Cdk1/B with an IC50 of 20 nM and displays increased potency over purvalanol A (Cat. No. 540500; IC50 = 50 nM), Roscovitine (Cat. No. 557360; IC50 = 450 nM), Bohemine (Cat. No. 203600; IC50 = 1.1 µM) and Olomoucine (Cat. No. 495620; IC50 = 7.0 µM). Further, exerts greater in vitro cytotoxicity in various cancer cell lines (IC50 = 3.0 µM, 5.3 µM, 6.3 µM, 6.3 µM and 11.1 µM for CEM, MCF7, HOS, G631 and K562, respectively).
    产品目录编号 495621
    品牌系列 Calbiochem®
    同义词 6-(2-Hydroxybenzylamino)-2-((1R)-(hydroxymethyl)propyl)amino)-9-isopropylpurine
    参考
    参考 Krystof, V., et al. 2002. Bioorg. Med. Chem. Lett. 12, 3283.
    产品信息
    CAS号 500735-47-7
    具有ATP竞争性 Y
    形式 Colorless solid
    Hill配方 C₁₉H₂₆N₆O₂
    化学配方 C₁₉H₂₆N₆O₂
    Molar Mass 370.5
    可逆 Y
    结构配方图像
    生物信息
    主靶 Cdk1/B
    主靶IC50 20 nM against Cdk1/B
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,495621,Olomoucine II - CAS 500735-47-7 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,14-688,PKG1α Protein, active, 10 µg
下一件merck millipore产品：merck millipore,默克密理博,CBL553,Anti-CD63 Antibody, clone RFAC4


相关产品

merck millipore,默克密理博,PF048,Heregulin, Human, Recombinant, E. coli merck millipore,默克密理博,PF048,Heregulin, Human, Recombinant, E. coli

merck millipore,默克密理博,ABE18-S,Anti-acetyl Histone H3 (Lys9) Antibody, Trial Size merck millipore,默克密理博,ABE18-S,Anti-acetyl Histone H3 (Lys9) Antibody, Trial Size

merck millipore,默克密理博,07-473,Anti-trimethyl-Histone H3 (Lys4) Antibody merck millipore,默克密理博,07-473,Anti-trimethyl-Histone H3 (Lys4) Antibody

merck millipore,默克密理博,324691,Elastatinal - CAS 51798-45-9 - Calbiochem merck millipore,默克密理博,324691,Elastatinal - CAS 51798-45-9 - Calbiochem

merck millipore,默克密理博,14-688,PKG1α Protein, active, 10 µg merck millipore,默克密理博,14-688,PKG1α Protein, active, 10 µg

merck millipore,默克密理博,CBL553,Anti-CD63 Antibody, clone RFAC4 merck millipore,默克密理博,CBL553,Anti-CD63 Antibody, clone RFAC4

merck millipore,默克密理博,511071,PAF Receptor Antagonist, ABT-491 - CAS 189689-94-9 - Calbiochem merck millipore,默克密理博,511071,PAF Receptor Antagonist, ABT-491 - CAS 189689-94-9 - Calbiochem

merck millipore,默克密理博,07-1341,Anti-PHLPP1 Antibody merck millipore,默克密理博,07-1341,Anti-PHLPP1 Antibody

merck millipore,默克密理博,SF-1753,ITGA10; Human, Cyanine 5 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-1753,ITGA10; Human, Cyanine 5 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,ABT160,Anti-Obscurin Antibody merck millipore,默克密理博,ABT160,Anti-Obscurin Antibody


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部