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纯度 ≥90% by SDS-PAGE 描述 概述 Recombinant, human neuregulin 1-β1/heregulin 1-β1 extracellular domain (NRG1-beta1/HRG1-beta1 ECD) consisting of amino acids 2-246 and expressed in E. coli. All NRG1 isoforms contain an EGF-like domain (β-splice variant) that is used to directly bind to the ErbB3 or ErbB4 receptor tyrosine kinases. 产品目录编号 492028 品牌系列 Calbiochem®
参考 参考 Buonanno, A., and G.D Fischbach 2001. Curr. Opin. Neurobiol. 11, 287.
Adlkofer, K. and C. Lai 2000. Glia 29, 104.
Garratt, A.N. et al., 2000. BioEssays 22, 987.
Karey, K.P., et al. 1988. Cancer Res. 48, 4083.产品信息 形式 Lyophilized 配方 Lyophilized from 0.2 µm filtered acetonitrile, TFA, BSA. Molar Mass 26900 生物信息 生物活性 ED₅₀ = 2.5-12.5 ng/ml as measured in a serum-free proliferation assay using MCF7 human breast adenocarcinoma cells. 纯度 ≥90% by SDS-PAGE 理化信息 污染物 Endotoxin: ≤1.0 EU/µg protein 溶解度 PBS 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution refrigerate (4°C) for short term-storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
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