merck millipore,默克密理愽
  • merck millipore,默克密理博,483400,7-Nitroindazole - CAS 2942-42-9 - Calbiochem

  • merck millipore,默克密理博,483400,7-Nitroindazole - CAS 2942-42-9 - Calbiochem

    产品名称：7-Nitroindazole - CAS 2942-42-9 - Calbiochem
    产品型号：483400
    A cell-permeable, reversible and competitive inhibitor of nitric oxide synthase (NOS) with high selectivity for the brain enzyme (IC₅₀ = 710 nM) vs.

    merck millipore,默克密理博,483400,7-Nitroindazole - CAS 2942-42-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,483400,7-Nitroindazole - CAS 2942-42-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₇H₅N₃O₂2942-42-9
    描述
    概述 A cell-permeable, reversible and competitive inhibitor of nitric oxide synthase (NOS) with high selectivity for the brain enzyme (IC50 = 710 nM) vs. iNOS (IC50 = 20 µM). Also inhibits bovine endothelial nitric oxide synthase (IC50 = 800 nM). Binds to the heme group of NOS.
    产品目录编号 483400
    品牌系列 Calbiochem®
    同义词 7-Ni
    参考
    参考 Schulz, J.B., et al. 1995. J. Neurochem. 64, 936.
    Klatt, P., et al. 1994. J. Biol. Chem. 269, 13861.
    Wolff, D.J., et al. 1994. Arch. Biochem. Biophys. 314, 360.
    Babbedge, R.C., et al. 1993. Br. J. Pharmacol. 110, 225.
    Moore, P.K., et al. 1993. Br. J. Pharmacol. 108, 296.
    产品信息
    CAS号 2942-42-9
    具有ATP竞争性 Y
    形式 Yellowish brown solid
    Hill配方 C₇H₅N₃O₂
    化学配方 C₇H₅N₃O₂
    Molar Mass 163.1
    可逆 Y
    结构配方图像
    生物信息
    主靶 NOS
    主靶IC50 710 nM against the brain enzyme nitric oxide synthase (NOS)
    纯度 ≥97% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or MeOH
    GHS安全信息
    RTECS NK7962200
    安全信息
    R相 R: 40-60

    Limited evidence of a carcinogenic effect.
    May impair fertility.
    S相 S: 53-22-36/37/39-45

    Avoid exposure - obtain special instructions before use.
    Do not breathe dust.
    Wear suitable protective clothing, gloves and eye/face protection.
    In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Carcinogenic / Teratogenic
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    From Catalog:
    Desc. Field- added "cell-permeable

    merck millipore,默克密理博,483400,7-Nitroindazole - CAS 2942-42-9 - Calbiochem

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