merck millipore,默克密理愽
  • merck millipore,默克密理博,480743,Neuronal Differentiation Inducer III - CAS 832115-62-5 - Calbiochem

  • merck millipore,默克密理博,480743,Neuronal Differentiation Inducer III - CAS 832115-62-5 - Calbiochem

    产品名称：Neuronal Differentiation Inducer III - CAS 832115-62-5 - Calbiochem
    产品型号：480743
    A cell-permeable isoxazole compound that selectively induces robust neuronal differentiation (Effective concentration = 20 µM) in various stem/progenitor cells.

    merck millipore,默克密理博,480743,Neuronal Differentiation Inducer III - CAS 832115-62-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,480743,Neuronal Differentiation Inducer III - CAS 832115-62-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₁H₁₀N₂O₂S832115-62-5
    描述
    概述 A cell-permeable isoxazole compound that selectively induces robust neuronal differentiation (Effective concentration = 20 µM) in various stem/progenitor cells. Induces insulin expression, and activates ERK signaling and histone acetylation in MIN6 pancreatic β cells. The underlying excitation-neurogenesis signaling is comprised of, at least in part, an initial NMDA receptor- and L-type chanenels-mediated Ca2+ influx, followed by an activation of CaMKII, phosphorylation/nuclear export of the MEF2 repressor HDAC5, the subsequent de-repression of MEF2, and the eventual activation of the HDAC-MEF2 epigenetic/transcriptional regulatory network.
    产品目录编号 480743
    品牌系列 Calbiochem®
    同义词 N-Cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide, Isx
    参考
    参考 Dioum, E.M., et al. 2011. Proc. Natl. Acad. Sci. USA 108, 20713.
    Zhang, L., et al. 2011. Differentiation 81, 233.
    Sadek, H., et al. 2008. Proc. Natl. Acad. Sci. USA 105, 6063.
    Schneider, J.W., et al. 2008. Nat. Chem. Biol. 4, 408.
    产品信息
    CAS号 832115-62-5
    形式 Off-white solid
    Hill配方 C₁₁H₁₀N₂O₂S
    化学配方 C₁₁H₁₀N₂O₂S
    Molar Mass 234.3
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,480743,Neuronal Differentiation Inducer III - CAS 832115-62-5 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,06-1333,Anti-phospho-TAB1 (Ser438) Antibody
下一件merck millipore产品：merck millipore,默克密理博,46-651MAG,MILLIPLEX MAP Phospho c-Met/HGFR (panTyr) Magnetic Bead MAPmate™ - Cell Signaling Multiplex Assay


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