merck millipore,默克密理博,48-610MAG,MILLIPLEXMAP STAT Cell Signaling Magnetic Bead 5-Plex Kit

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Merck Millipore 默克密理愽

merck millipore,默克密理博,48-610MAG,MILLIPLEXMAP STAT Cell Signaling Magnetic Bead 5-Plex Kit - Cell Signaling Multiplex Assay

可用的分析物	品种反应性	主要应用	检测方法
STAT6 (Tyr641), STAT1 (Tyr701), STAT2 (Tyr690), STAT3 (Tyr705), STAT5A/B (Tyr694/699)	H	Mplex	Luminex xMAP

描述
产品目录编号	48-610MAG
商名	MILLIPLEX
描述	MILLIPLEXMAP STAT Cell Signaling Magnetic Bead 5-Plex Kit - Cell Signaling Multiplex Assay
概述	The STAT (Signal Transducers and Activators of Transcription) family, consisting of seven mammalian members, regulates many aspects of growth, survival and differentiation in cells. The extracellular binding of cytokines, hormones, growth factors and neurotransmitters to receptors induces phosphorylation of the intracellular Janus kinases (JAKs) that, in turn, phosphorylate STAT proteins at conserved tyrosine residues, activating SH2-mediated dimerization followed by translocation to the nucleus. STAT dimers then bind to IRE (interferon response element) and GAS (gamma interferon-activated sequence) DNA elements, resulting in the transcriptional regulation of downstream genes.

应用
应用	The analytes available for this multiplex kit are: STAT1 (Tyr701), STAT2 (Tyr690), STAT3 (Tyr705), STAT5A/B (Tyr694/699), STAT6 (Tyr641).
主要应用	Multiplexing
应用说明	• An overnight (4°C) incubation is recommended for best results. • This assay requires 25 µL diluted cell lysate per well. • This kit must be run using Assay Buffer 1 (provided). • 1 - 25 μg cell lysate/well (recommended starting concentration is 40 to 1,000 μg protein/mL).

生物信息
特异性	Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
品种反应性	Human
可用的分析物	STAT6 (Tyr641) STAT1 (Tyr701) STAT2 (Tyr690) STAT3 (Tyr705) STAT5A/B (Tyr694/699)

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Recommended storage for kit components is 2 - 8°C.

包装信息
数量	96-well plate
包装	96-well plate

merck millipore,默克密理博,48-610MAG,MILLIPLEXMAP STAT Cell Signaling Magnetic Bead 5-Plex Kit - Cell Signaling Multiplex Assay

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