• merck millipore,默克密理博,539578,PKG, Iα, Bovine Lung
  • merck millipore,默克密理博,539578,PKG, Iα, Bovine Lung

    产品名称:PKG, Iα, Bovine Lung
    产品型号:539578


    merck millipore,默克密理博,539578,PKG, Iα, Bovine Lung

  • 产品介绍
  • merck millipore,默克密理博,539578,PKG, Iα, Bovine Lung

    描述
    概述 Native PKGIα purified from bovine lung. PKG is involved in regulation of smooth muscle relaxation, platelet function, and cell division. PKG is activated by binding of cGMP to regulatory subunits within the holoenzyme, but in contrast to PKA, the activation of PKG does not invlove physical dissociation of catalytic from the regulatory domains. The activated enzyme phosphorylates target proteins at serine and/or threonine residues that are found within the recognition motif, Arg-Lys-Arg-Ser*-Arg-Ala-Glu.
    Note: 4µg = 6000 units.
    产品目录编号 539578
    品牌系列 Calbiochem®
    同义词 cGMP-Dependent Protein Kinase Catalytic Subunit, PKG Catalytic Subunit, Protein Kinase G Iα
    应用数据
    参考
    参考 Brophy, M.C., et al. 2006. J. Vasc. Res. 39, 95.
    Colbran J.L., et al. 1992. J. Biol. Chem. 267, 9589.
    Corbin, J.D. and Doskeland, S.O. 1983. J Biol Chem 258, 11391.
    Witt, J.J. and Roskoski, R., Jr, 1975. Anal Biochem 66, 253.
    产品信息
    形式 Liquid
    配方 In 150 mM NaCl, 25 mM β-mercaptoethanol, 10 mM K₂HPO₄, 1 mM EDTA, 12% sucrose, pH 6.8.
    Molar Mass 78000
    生物信息
    特异活性 ≥1300 units/µg enzyme
    浓缩标签 Please refer to vial label for lot-specific concentration
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Standard Handling
    储存 ≤ -70°C
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C).

    merck millipore,默克密理博,539578,PKG, Iα, Bovine Lung

上一件merck millipore产品:merck millipore,默克密理博,407306,γ-Interferon, Human, Recombinant, E. coli
下一件merck millipore产品:merck millipore,默克密理博,48-610MAG,MILLIPLEXMAP STAT Cell Signaling Magnetic Bead 5-Plex Kit - Cell Signaling Multiplex Assay



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