merck millipore,默克密理博,IL006,Interleukin-6 Protein, Recombinant human

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merck millipore,默克密理博,IL006,Interleukin-6 Protein, Recombinant human
产品名称：Interleukin-6 Protein, Recombinant human
产品型号：IL006
The recombinant human Interleukin-6 protein (or IL-6 protein) is a potent lymphoid cell growth factor which affects B-lymphocytes, T-lymphocytes & hybridoma cells.

merck millipore,默克密理博,IL006,Interleukin-6 Protein, Recombinant human

产品介绍

merck millipore,默克密理博,IL006,Interleukin-6 Protein, Recombinant human

重要规格表

主要应用	品种	纯度
CULT	Human	Greater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of IFN gamma.

描述
产品目录编号	IL006
品牌系列	Chemicon®
商名	Chemicon
描述	Interleukin-6 Protein, Recombinant human
概述	Interleukin-6 (IL-6) is a potent lymphoid cell growth factor which affects B-lymphocytes, T-lymphocytes and hybridoma cells. It will also affect cytotoxic T-cells in combination with other factors such as IL-2 and g-interferon. Human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.
Alternate Names	IL-6

产品信息
演示	Lyophilized from 10 mM Sodium Citrate, pH 3.0.

应用
应用	The recombinant human Interleukin-6 protein (or IL-6 protein) is a potent lymphoid cell growth factor which affects B-lymphocytes, T-lymphocytes & hybridoma cells.
主要应用	Cell Culture
应用说明	For most in vitro applications, IL-6 exerts its biological activity in the concentration range of 0.1 to 10.0 ng/mL. Responding cells are (partial list): B-cells, hybridoma cells.

生物信息
纯度	Greater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of IFN gamma.
品种	Human
特异活性	Human IL-6 is fully biologically active when compared to standards. The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6-dependent mouse 7TD1 cells is <= 0.1 ng/mL, corresponding to a specific activity of >= 1 x 10(E7) units/mg.
Entrez基因编号	NM_000600.2
基因符号	IFNB2 HGF IL6 IL-6 HSF BSF2 BSF-2 CDF
UniProt编号	P05231
UniProt汇总	FUNCTION: SwissProt: P05231 # IL-6 is a cytokine with a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, it induces nerve cells differentiation, in hepatocytes it induces acute phase reactants. SIZE: 212 amino acids; 23718 Da SUBCELLULAR LOCATION: Secreted. PTM: N- and O-glycosylated. DISEASE: SwissProt: P05231 # Genetic variations in IL6 are associated with susceptibility to systemic juvenile rheumatoid arthritis [MIM:604302]. Systemic juvenile rheumatoid arthritis is juvenile chronic arthritis associated with severe, debilitating, extraarticular features, and occasionally fatal complications. Despite medical treatment, many children still experience early joint destruction, necessitating surgical replacement. & At least 1 polymorphism in the IL6 gene renders HIV- infected men susceptible to Kaposi sarcoma [MIM:148000]. Kaposi sarcoma is a sarcoma of spindle cells mixed with angiomatous tissue. A relatively rare malignant skin tumor that results in multifocal purplish coloured papules or plaques that eventually form nodules. Most commonly seen in patients who suffer from AIDS. SIMILARITY: SwissProt: P05231 ## Belongs to the IL-6 superfamily.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	The lyophilized protein is stable for a few weeks at room temperature, but is best stored at -20°C. After a quick spin, reconstitute in 5-10 mM Acetic Acid to a concentration of 0.1-0.5 mg/mL. Note: Gently shake the solution for about 10 minutes for better solubility. This solution can then be further diluted into aqueous buffers and stored in aliquots at 4°C for 1 week or at -20°C for up to 6 months.

储存和货运信息

存储条件

The lyophilized protein is stable for a few weeks at room temperature, but is best stored at -20°C. After a quick spin, reconstitute in 5-10 mM Acetic Acid to a concentration of 0.1-0.5 mg/mL. Note: Gently shake the solution for about 10 minutes for better solubility. This solution can then be further diluted into aqueous buffers and stored in aliquots at 4°C for 1 week or at -20°C for up to 6 months.