• merck millipore,默克密理博,475913,Mycophenolic Acid - CAS 24280-93-1 - Calbiochem
  • merck millipore,默克密理博,475913,Mycophenolic Acid - CAS 24280-93-1 - Calbiochem

    产品名称:Mycophenolic Acid - CAS 24280-93-1 - Calbiochem
    产品型号:475913
    An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the formation of XMP and GMP.

    merck millipore,默克密理博,475913,Mycophenolic Acid - CAS 24280-93-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,475913,Mycophenolic Acid - CAS 24280-93-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₇H₂₀O₆24280-93-1
    描述
    概述 An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the formation of XMP and GMP. Useful for selection of animal cells that express the E. coli gene coding for xanthine-guanine phosphoribosyltransferase. Also suppresses cytokine-induced nitric oxide production in mouse and rat vascular endothelial cells.
    产品目录编号 475913
    品牌系列 Calbiochem®
    同义词 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic Acid, MPA
    参考
    参考 Langman, L.J., et al. 1995. Clin. Chem. 41, 295.
    Senda, M., et al. 1995. Transplantation 60, 1143.
    Warner-Bartnicki, A.L., et al. 1993. Exp. Cell Res. 204, 241.
    Falkner, F.G., and Moss, B. 1988. J. Virol. 62, 1849.
    Cohen, M.B., et al. 1981. J. Biol. Chem. 256, 8713.
    Mulligan, R.C., and Berg, P. 1981. Proc. Natl. Acad. Sci. USA 78, 2072.
    产品信息
    CAS号 24280-93-1
    具有ATP竞争性 N
    形式 White to off-white solid
    Hill配方 C₁₇H₂₀O₆
    化学配方 C₁₇H₂₀O₆
    Molar Mass 320.4
    可逆 N
    结构配方图像
    生物信息
    主靶 Inosine monophosphate dehydrogenase
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 EtOH or 0.1 N NaOH
    GHS安全信息
    RTECS MP8050000
    安全信息
    R相 R: 20/21/22-40

    Harmful by inhalation, in contact with skin and if swallowed.
    Limited evidence of a carcinogenic effect.
    S相 S: 22-36

    Do not breathe dust.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful & Carcinogenic / Teratogenic
    储存 +15°C to +30°C
    无需冷冻 No
    特殊指南 Following reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

    merck millipore,默克密理博,475913,Mycophenolic Acid - CAS 24280-93-1 - Calbiochem

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