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品种反应性 主要应用 宿主 格式 抗体类型 H ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT405 描述 Anti-KIF5 Antibody Alternate Names - KIF5A
- Kinesin heavy chain isoform 5A
- Kinesin heavy chain neuron-specific 1
- Neuronal kinesin heavy chain
- NKHC
背景信息 Kinesin heavy chain isoform 5A, also known as Kinesin heavy chain neuron-specific 1 or Neuronal kinesin heavy chain (NKHC), and encoded by the gene name KIF5A or NKHC1, are members of the kinesin superfamily of proteins (KIFs). These proteins are microtubuledependent motors that slide along microtubules and transport cellular organelles and mRNA to different parts of the cell. In neurons, KIF5 performs this role in an anterograde fashion from the neuronal cell body to axonal or dendritic terminals. KIF5 was initially differentiated from the ubiquitously expressed kinesin as being highly enriched in subsets of neurons and selectively concentrated in the cell body. KIF5 has at least three known isoforms; KIF5A (117 kDa), KIF5B (39 kDa), and KIF5C (39 kDa). Mutations in one of the isoforms of KIF5 (KIF5A) is thought to be involved in hereditary spastic paraplegias 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-KIF5 Antibody is an antibody against KIF5 for use in western blotting, ICC & immunofluorescence. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry Analysis: 5 μg/mL from a representative lot detected KIF5 in K562 cells.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected KIF5 in K562 cells.生物信息 免疫原品种 KLH-conjugated synthetic peptide corresponding to the C-terminus of human KIF5. 表位 C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes all isoforms of KIF5. 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - NKHC1
- KIF5A
纯化方法 Affinity UniProt编号 - Q12840
产品使用声明 质量保证 Evaluated by Western Blotting in K562 cell lysate.
Western Blotting Analysis: 1 μg/mL of this antibody detected KIF5 in K562 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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