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merck millipore,默克密理博,475878,(+)-MK 801 Maleate - CAS 77086-22-7 - Calbiochem
产品名称：(+)-MK 801 Maleate - CAS 77086-22-7 - Calbiochem
产品型号：475878
A highly potent, selective, and non-competitive NMDA receptor antagonist that acts by binding to a site located within the NMDA-associated ion channel, thus preventing Ca2+ flux.
merck millipore,默克密理博,475878,(+)-MK 801 Maleate - CAS 77086-22-7 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₆H₁₅N · C₄H₄O₄ 77086-22-7 描述 概述 A highly potent, selective, and non-competitive NMDA receptor antagonist that acts by binding to a site located within the NMDA-associated ion channel, thus preventing Ca2+ flux. An effective anti-ischemic agent in several animal models. Has been used to develop an in vivo model of NMDA receptor-dependent apoptotic neurodegenerative disease in developing rat brains. Has also been used to develop an in vitro model of NMDA receptor-specific Ca2+ entry induced seizures. 产品目录编号 475878 品牌系列 Calbiochem®
同义词 (5R,10S)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]-cyclohepten-5-10-imine, Maleate, Dizocilpine Maleate, NMDA Antagonist I 参考 参考 Ikonomidou, C., et al. 1999. Science 283, 70.
DeLorenzo, R.J., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 14482.
Woodruff, G.N., et al. 1987. Neuropharmacology 26, 903.
Wong, E.H.F., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 7104.产品信息 CAS号 77086-22-7 形式 White solid Hill配方 C₁₆H₁₅N · C₄H₄O₄ 化学配方 C₁₆H₁₅N · C₄H₄O₄ Molar Mass 337.4 可逆 N 结构配方图像 生物信息 主靶 NMDA receptor 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 EtOH or H₂O 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
防潮 Protect from moisture
无需冷冻 No
特殊指南 Following reconstitution in water refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Aqueous stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
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