merck millipore,默克密理愽
  • merck millipore,默克密理博,475863,MK2a Inhibitor - CAS 41179-33-3 - Calbiochem

  • merck millipore,默克密理博,475863,MK2a Inhibitor - CAS 41179-33-3 - Calbiochem

    产品名称：MK2a Inhibitor - CAS 41179-33-3 - Calbiochem
    产品型号：475863
    The MK2a Inhibitor, also referenced under CAS 41179-33-3, controls the biological activity of MK2a. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications More>>

    merck millipore,默克密理博,475863,MK2a Inhibitor - CAS 41179-33-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,475863,MK2a Inhibitor - CAS 41179-33-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₂H₂₀FNO₂41179-33-3
    描述
    概述 A reversible p-amidophenolic compound that selectively inhibits the phosphorylation of MK2a (mitogen-activated protein kinase-activated protein kinase 2a; Kiapp = 330 nM) by p38α in a non-ATP-competitive manner. Does not block the kinase activity of p38α towards the other two known p38 substrates, MBP and ATF-2.
    产品目录编号 475863
    品牌系列 Calbiochem®
    同义词 Mitogen-activated protein kinase-activated protein kinase 2a Inhibitor, 4-(2ʹ-Fluorobiphenyl-4-yl)-N-(4-hydroxyphenyl)-butyramide, CMPD1, MAPKAPK2a Inhibitor
    参考
    参考 Davidson, W., et al. 2004. Biochemistry 43, 11658.
    Lukas, S.M., et al. 2004. Biochemistry 43, 9950.
    产品信息
    CAS号 41179-33-3
    具有ATP竞争性 N
    形式 Pale yellow solid
    Hill配方 C₂₂H₂₀FNO₂
    化学配方 C₂₂H₂₀FNO₂
    Molar Mass 349.4
    可逆 Y
    结构配方图像
    生物信息
    主靶 Mk2α
    主靶Ki Kiapp = 330 nM against mitogen-activated protein kinase-activated protein kinase 2a (MK2a)
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,475863,MK2a Inhibitor - CAS 41179-33-3 - Calbiochem

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