merck millipore,默克密理愽
  • merck millipore,默克密理博,454870,MARK/Par-1 Activity Inhibitor, 39621 - Calbiochem

  • merck millipore,默克密理博,454870,MARK/Par-1 Activity Inhibitor, 39621 - Calbiochem

    产品名称：MARK/Par-1 Activity Inhibitor, 39621 - Calbiochem
    产品型号：454870
    The MARK/Par-1 Activity Inhibitor, 39621 controls the biological activity of MARK/Par-1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,454870,MARK/Par-1 Activity Inhibitor, 39621 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,454870,MARK/Par-1 Activity Inhibitor, 39621 - Calbiochem

    重要规格表

    经验配方
    C₂₁H₂₁N₃O₃S
    描述
    概述 A cell-permeable dihydropyrazinyl-thioacetamide that acts as an ATP-competitive MARK-selective inhibitor (IC50 = 3.6 µM; [ATP] = 100 µM). Shown to effectively block primary rat cortical neuron axon growth (5.7 µm/hr vs 32.5 µm/hr with or without 20 µM inhibitor) and prevent MARK2 overexpression-induced Tau Ser262 phosphorylation and cytotoxicity in CHO cells (10 µM).
    产品目录编号 454870
    品牌系列 Calbiochem®
    同义词 N-(2,5-Dimethylphenyl)-2-(4-(4-methoxyphenyl)-3-oxo-3,4-dihydropyrazin-2-ylthio)acetamide, Microtubule Affinity Regulating Kinase Inhibitor, MAP Affinity Regulating Kinase Inhibitor, PAR1 Inhibitor
    参考
    参考 Timm, T., et al. 2011. J. Biol. Chem. 286, 41711.
    产品信息
    形式 Beige solid
    Hill配方 C₂₁H₂₁N₃O₃S
    化学配方 C₂₁H₂₁N₃O₃S
    Molar Mass 395.5
    结构配方图像
    生物信息
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,454870,MARK/Par-1 Activity Inhibitor, 39621 - Calbiochem

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