merck millipore,默克密理愽
  • merck millipore,默克密理博,444805,Membrane Traffic Inhibitor, A5 - Calbiochem

  • merck millipore,默克密理博,444805,Membrane Traffic Inhibitor, A5 - Calbiochem

    产品名称：Membrane Traffic Inhibitor, A5 - Calbiochem
    产品型号：444805
    The Membrane Traffic Inhibitor, A5 controls the biological activity of adaptor complex AP-1.

    merck millipore,默克密理博,444805,Membrane Traffic Inhibitor, A5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,444805,Membrane Traffic Inhibitor, A5 - Calbiochem

    重要规格表

    经验配方
    C₁₇H₂₄N₂O • HCl
    描述
    概述 A cell-permeable piperazinyl compound that specifically blocks clathrin adaptor complex AP-1-dependent traffic between trans-Golgi network (TGN) and endosomes in budding yeast, while exhibiting little effects against other trafficking pathways involving TGN and endosomes. Inhibits growth of yeast cells lacking complementary GGA1/2 adaptor proteins (EC50 = 50 µM), but not wild-type or AP-1-deficient cells even at concentrations as high as 300 µM. A5 presumably acts at a stage after AP-1 membrane recruitment as evidenced by an enhanced AP-1 perinuclear localization upon A5 treatment of HeLa cells.
    产品目录编号 444805
    品牌系列 Calbiochem®
    同义词 1-(4-(4-(E-2-Methyl-2-butenyl)piperazinyl)phenyl)ethanone, HCl, 5431942, A5
    参考
    参考 Duncan, M.C., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 6235.
    产品信息
    形式 Pale yellow solid
    Hill配方 C₁₇H₂₄N₂O • HCl
    化学配方 C₁₇H₂₄N₂O • HCl
    Molar Mass 308.9
    吸湿 Hygroscopic
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,444805,Membrane Traffic Inhibitor, A5 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,AG983,PAX6 Control Peptide for AB5409
下一件merck millipore产品：merck millipore,默克密理博,676500,VEGFR2/Flt3/c-Kit Inhibitor - CAS 796967-10-7 - Calbiochem


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