merck millipore,默克密理愽
  • merck millipore,默克密理博,444289,Marimastat - CAS 154039-60-8 - Calbiochem

  • merck millipore,默克密理博,444289,Marimastat - CAS 154039-60-8 - Calbiochem

    产品名称：Marimastat - CAS 154039-60-8 - Calbiochem
    产品型号：444289
    An orally active peptidyl hydroxamate-based broad-spectrum MMP inhibitor that targets both the substrate binding site and the active-site Zn2+.

    merck millipore,默克密理博,444289,Marimastat - CAS 154039-60-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,444289,Marimastat - CAS 154039-60-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₅H₂₉N₃O₅154039-60-8
    描述
    概述 An orally active peptidyl hydroxamate-based broad-spectrum MMP inhibitor (IC50 in nM = 5, 6, 200, 20, 2, 1.8 and 3.8 for MMP-1, -2, -3, -7, -8, -14 and TACE, respectively) that targets both the substrate binding site and the active-site Zn2+. Marimastate is widely used in studying the involvement of MMPs in various cellular and pathological processes both in vitro and in vivo.
    产品目录编号 444289
    品牌系列 Calbiochem®
    同义词 (2S,3R)-N⁴-((1S)-2,2-Dimethyl-1-((methylamino)carbonyl)propyl)-N¹,2-hydroxy-3-(2-methylpropyl)butanediamide, BB-2516
    参考
    参考 Hansen, H.P., et al. 2002. Int. J. Cancer 98, 210.
    Tsuji, F., et al. 2002. Cytokine 17, 294.
    Barlaam, B., et al. 1999. J. Med. Chem. 42, 4890.
    Whittaker, M., et al. 1999. Chem. Rev. 99, 2735.
    Rasmussen, H.S., and McCann, P.P. 1997. Pharmacol. Ther. 75, 69.
    产品信息
    CAS号 154039-60-8
    形式 White solid
    Hill配方 C₁₅H₂₉N₃O₅
    化学配方 C₁₅H₂₉N₃O₅
    Molar Mass 331.4
    结构配方图像
    生物信息
    纯度 ≥98% by NMR
    理化信息
    溶解度 DMSO
    安全信息
    S相 S: 22-24/25-36/37/39

    Do not breathe dust.
    Avoid contact with skin and eyes.
    Wear suitable protective clothing, gloves and eye/face protection.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,444289,Marimastat - CAS 154039-60-8 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,648466,TRITON X-100 Detergent, Molecular Biology Grade - CAS 9002-93-1 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,8325-OP,OmniPur TBS 20X Ready Pack Powder - Calbiochem


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