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描述 概述 Full-length recombinant, human MMP-13 fused to a His•Tag® sequence and expressed in S. frugiperda insect cells. This 452 amino acid proenzyme contains the N-terminal propeptide, the Ca2+- and Zn2+-binding catalytic domain, the hinge region, and the C-terminal hemopexin domain. Hydrolyzes collagen type II 5 to 6 times faster than collagens Type I and III. Exhibits high activity towards gelatin and degrades α1-antichymotrypsin and plasminogen activator inhibitor-2 (PAI-2). Note: 1 mU = 1 milliunit. 产品目录编号 444248 品牌系列 Calbiochem®
同义词 Collagenase-3 参考 参考 Herget, J., et al. 2003. Am. J. Physiol. 285, 4199.
Nagase, H. 1997. Biol. Chem. 378, 151.
Knäuper, V., et al. 1996. J. Biol. Chem. 271, 1544.
Knauper, V., et al. 1996. J. Biol. Chem. 271, 17124.
Pei, D., and Weiss, S.J. 1996. J. Biol. Chem. 271, 9135.
Knight, C.G., et al. 1992. FEBS Lett. 296, 263.产品信息 形式 Liquid 配方 In 150 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, pH 7.5. Molar Mass 60000 生物信息 纯度 ≥90% by SDS-PAGE 特异活性 ≥50 mU/mg protein 储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C).
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