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纯度 ≥95% by SDS-PAGE 描述 概述 Recombinant, murine lumican, consisting of amino acids 19-338, fused at the C-terminus to a His•Tag® sequence, and expressed in NS0-derived mouse myeloma cells. Lumincan a 40-kDa member of the small leucine-rich repeat proteoglycans (SLRPs) family/Class II subfamily of proteins. It is known for its ability to modulate collagen fibrillogenesis and role in cell proliferation regulation. 产品目录编号 440319 品牌系列 Calbiochem®
参考 参考 D'Onofrio, M.F. et al. 2008. Biochem. Biophys. Res. Commun. 365, 266.
Nikitovic, D. et al. 2008. IUBMB Life 60, 818.
Nikitovic, D. et al. 2008. FEBS J. 275, 350.
Ishiwata, T. et al. 2007. Oncol. Rep. 18, 537.
Vuillermoz, B. et al. 2004. Exp. Cell Res. 296,294.
Chakravarti, S. et al. 2003. Invest. Ophthalmol. Vis. Sci. 44, 2422.
Jepsen, K.J. et al. 2002. J. Biol. Chem. 277, 35532.
Chakravarti, S. et al. 2000. Invest. Ophthalmol. Vis. Sci. 41,3365.
Blochberger, T.C. et al. 1992. J. Biol. Chem. 267, 347.
Chakravarti, S. et al. 1998. J. Cell Biol. 141, 1277.产品信息 形式 Lyophilized 配方 Lyophilized from 0.2 µm filtered PBS. Molar Mass 37300 生物信息 生物活性 Cell adhesion: 50-70% after 50 min at 37°C as measured by the ability of immobilized lumican to supoprt the adhesion of 5 X 10⁴ BCE C/D-1b bovine cornea-derived endothelial cells. 纯度 ≥95% by SDS-PAGE 理化信息 污染物 Endotoxin: ≤1.0 EU/µg protein 溶解度 PBS 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
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