merck millipore,默克密理博,437725,Lipoxin A₄, 15-epi - CAS 171030-11-8

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merck millipore,默克密理博,437725,Lipoxin A₄, 15-epi - CAS 171030-11-8 - Calbiochem
产品名称：Lipoxin A₄, 15-epi - CAS 171030-11-8 - Calbiochem
产品型号：437725
A epimeric lipoxin A4 analog that is more potent and metabolically stable than LXA4.

merck millipore,默克密理博,437725,Lipoxin A₄, 15-epi - CAS 171030-11-8 - Calbiochem

产品介绍

merck millipore,默克密理博,437725,Lipoxin A₄, 15-epi - CAS 171030-11-8 - Calbiochem

重要规格表

经验配方	CAS号
C₂₀H₃₂O₅	171030-11-8

描述
概述	A epimeric lipoxin A₄ (Cat. No. 437720) analog that is more potent and metabolically stable than LXA₄. Exhibits anti-inflammatory properties and serves as a "stop signal" to excessive leukocyte trafficking/infiltration. Blocks TNF-α-induced IL-8 release in human enterocyte. It is also an important modulator of the many pharmacological actions caused by aspirin.
概述	Caution! Product contains volatile liquid. Keep product cold at all times.
产品目录编号	437725
品牌系列	Calbiochem®
同义词	LXA₄-15-epi, 15(R)-LXA₄, Aspirin-triggered LXA₄, (5S,6R,15R)-5,6,15-Trihydroxy-7,9,13-trans-11-cis-eicosatetraenoic acid

参考
参考	Wallace, J.L., and Fiorucci, S. 2003. Trends Pharmacol. Sci. 24, 323. Filep, J.G., et al. 2002. Adv. Exp. Med. Biol. 507, 223. Titos, E., et al. 1999. Am. J. Physiol. 277, C870. Gronert, K., et al. 1998. J. Exp. Med. 187, 1285. Maddox, J.F., et al. 1997. J. Biol. Chem. 272, 6972. Claria, J., et al. 1996. Mol. Med. 2, 583. Claria, J., and Serhan, C.N. 1995. Proc. Natl. Acad. Sci. USA 92, 9475. Serhan, C.N., et al. 1995. Biochemistry 34, 14609.

参考

Wallace, J.L., and Fiorucci, S. 2003. Trends Pharmacol. Sci. 24, 323.
Filep, J.G., et al. 2002. Adv. Exp. Med. Biol. 507, 223.
Titos, E., et al. 1999. Am. J. Physiol. 277, C870.
Gronert, K., et al. 1998. J. Exp. Med. 187, 1285.
Maddox, J.F., et al. 1997. J. Biol. Chem. 272, 6972.
Claria, J., et al. 1996. Mol. Med. 2, 583.
Claria, J., and Serhan, C.N. 1995. Proc. Natl. Acad. Sci. USA 92, 9475.
Serhan, C.N., et al. 1995. Biochemistry 34, 14609.

产品信息
CAS号	171030-11-8
具有ATP竞争性	N
形式	Liquid
配方	In Ethanol.
Hill配方	C₂₀H₃₂O₅
化学配方	C₂₀H₃₂O₅
Molar Mass	352.5
吸湿	Hygroscopic
可逆	N
结构配方图像

生物信息
主靶	Exhibits anti-inflammatory properties
纯度	≥98% by HPLC

理化信息
细胞可渗透	N

储存和货运信息
货运代码	Dry Ice Only
毒性	Flammable
有害材料注意事项：	Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存	≤ -70°C
避光	Protect from light
吸湿	Hygroscopic
无需冷冻	No
特殊指南	Following initial thaw aliquot and freeze (-70°C).