merck millipore,默克密理博,429705,Leptin, Mouse, Recombinant, E. coli

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Merck Millipore 默克密理愽

merck millipore,默克密理博,429705,Leptin, Mouse, Recombinant, E. coli
产品名称：Leptin, Mouse, Recombinant, E. coli
产品型号：429705

merck millipore,默克密理博,429705,Leptin, Mouse, Recombinant, E. coli

描述
概述	Recombinant, mouse leptin espressed in E. coli. Native leptin is a product of the obese (ob) gene that serves as a ligand for the OB receptor (OB-R). Mice with mutations in the ob gene have been found to be obese and diabetic and to have reduced activity, metabolism and body temperature. Suppresses insulin secretion by inhibiting activities of Ca²⁺-dependent PKC isoforms. Reported to reduce hepatic glucose production by blocking phosphoenolpyruvate synthesis.
产品目录编号	429705
品牌系列	Calbiochem®
同义词	βrmOB

参考
参考	Anderwald, C., et al. 2002. Mol. Endocrinol. 16, 1612. Ookuma, M., et al. 1998. Diabetes 47, 219. Campfield, L.A., et al. 1995. Science 269, 546. Halaas, J.L., et al. 1995. Science 269, 543. Pelleymounter, M.A., et al. 1995. Science 269, 540. Zhang, Y., et al. 1994. Nature 372, 425.

产品信息
CAS号	181030-10-4
形式	Lyophilized
配方	Lyophilized from a sterile filtered PBS.
Molar Mass	16000

生物信息
生物活性	ED₅₀ = 0.2-1 ng/ml as measured by its ability to induce proliferation of leptin-dependent rOB-R transfected murine BAF3 cells
纯度	≥97% by SDS-PAGE

理化信息
污染物	Endotoxin: ≤1.0 EU/µg leptin
溶解度	20 mM Tris-HCI, pH 8.0

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	≤ -70°C
无需冷冻	No
特殊指南	Following reconstitution, refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C or -70°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C or -70°C. Avoid freeze/thaw cycles of solutions.

merck millipore,默克密理博,429705,Leptin, Mouse, Recombinant, E. coli

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