merck millipore,默克密理博,ABE155,Anti-phospho Histone H3.1/H3.2 Antibody (Ser87)

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
B, H, M	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABE155
描述	Anti-phospho Histone H3.1/H3.2 Antibody (Ser87)
Alternate Names	Alpha-synuclein Non-A beta component of AD amyloid Non-A4 component of amyloid precursor NACP
背景信息	Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. Histone H3.1, H3.2 and H3.3 are all closely related Histone H3 variants, that despite differing by only a few amino acids have been shown to have different functional roles.

产品信息
格式	Affinity Purified
控制	HeLa acid extract
演示	Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Detect Histone H3 using this rabbit polyclonal antibody, Anti-phospho Histone H3.1/H3.2 Antibody (Ser87) validated for use in western blotting & Dot Blot.
主要应用	Western Blotting
应用说明	Dot Blot (Specificity) Analysis: 1µg/mL of this antibody detected phospho Histone H3.1/H3.2 (Ser87) in a panel of unmodified and modified Histones.

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to human Histone H3.1/H3.2 phosphorylated at Ser87.
表位	Phosphorylated at Ser87
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
特异性	This antibody recognizes Histone H3.1/H3.2 phosphorylated at Ser87. This antibody demonstrates specificity for phospho Histone H3.1/H3.2 (Ser87), but does not cross react with phospho Histone H3.3, or any other modified and non-modified histones.
品种反应性	BovineHumanMouse
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_003520
基因符号	PARK1 SNCA NACP
纯化方法	Affinity purified
UniProt编号	P68431

产品使用声明
质量保证	Evaluated by Western Blotting in Colcemid treated HeLa acid extract. Western Blotting Analysis: 0.5 µg/mL of this antibody detected phospho Histone H3.1/H3.2 (Ser87) in 10 µg of Colcemid treated HeLa acid extract
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,ABE155,Anti-phospho Histone H3.1/H3.2 Antibody (Ser87)

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