• merck millipore,默克密理博,422682,Kir1.1 Inhibitor, VU591 - Calbiochem
  • merck millipore,默克密理博,422682,Kir1.1 Inhibitor, VU591 - Calbiochem

    产品名称:Kir1.1 Inhibitor, VU591 - Calbiochem
    产品型号:422682
    The Kir1.1 Inhibitor, VU591 controls the biological activity of Kir1.1. This small molecule/inhibitor is primarily used for Neuroscience applications.

    merck millipore,默克密理博,422682,Kir1.1 Inhibitor, VU591 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,422682,Kir1.1 Inhibitor, VU591 - Calbiochem

    重要规格表

    经验配方
    C₁₆H₁₂N₆O₅
    描述
    概述 A cell-permeable, benzoimidazole, renal outer medullary potassium channel (ROMK) blocker that selectively inhibits inward rectifier potassium channel, Kir1.1 (IC50 = 240 nM), in HEK-293 cells. At 10 µM, it displays no effect on Kir2.1, Kir2.3, Kir4.1, and Kir7.1, with 150-fold selectivity over Kir6.2. In addition, it exhibits a modest off-target effect on the GABAA receptor (IC50 = 6.2 µM) among a panel of cardiac and central nervous system ion channels and receptors.
    产品目录编号 422682
    品牌系列 Calbiochem®
    同义词 Inward rectifier potassium channel Kir1.1 blocker, VU591
    参考
    参考 Bhave, G., et al. 2011. Mol Pharmacol. 79, 42.
    产品信息
    形式 Light gray solid
    Hill配方 C₁₆H₁₂N₆O₅
    化学配方 C₁₆H₁₂N₆O₅
    Molar Mass 368.3
    结构配方图像
    生物信息
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Regulatory Review
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,422682,Kir1.1 Inhibitor, VU591 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,05-117,Anti-FGF-2/basic FGF (neutralizing) Antibody, clone bFM-1
下一件merck millipore产品:merck millipore,默克密理博,ABS454,Anti-Aldh3A1 Antibody



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