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merck millipore,默克密理博,422682,Kir1.1 Inhibitor, VU591 - Calbiochem
产品名称:Kir1.1 Inhibitor, VU591 - Calbiochem
产品型号:422682
The Kir1.1 Inhibitor, VU591 controls the biological activity of Kir1.1. This small molecule/inhibitor is primarily used for Neuroscience applications.
merck millipore,默克密理博,422682,Kir1.1 Inhibitor, VU591 - Calbiochem
- 产品介绍
重要规格表
经验配方 C₁₆H₁₂N₆O₅ 描述 概述 A cell-permeable, benzoimidazole, renal outer medullary potassium channel (ROMK) blocker that selectively inhibits inward rectifier potassium channel, Kir1.1 (IC50 = 240 nM), in HEK-293 cells. At 10 µM, it displays no effect on Kir2.1, Kir2.3, Kir4.1, and Kir7.1, with 150-fold selectivity over Kir6.2. In addition, it exhibits a modest off-target effect on the GABAA receptor (IC50 = 6.2 µM) among a panel of cardiac and central nervous system ion channels and receptors. 产品目录编号 422682 品牌系列 Calbiochem®
同义词 Inward rectifier potassium channel Kir1.1 blocker, VU591 参考 参考 Bhave, G., et al. 2011. Mol Pharmacol. 79, 42. 产品信息 形式 Light gray solid Hill配方 C₁₆H₁₂N₆O₅ 化学配方 C₁₆H₁₂N₆O₅ Molar Mass 368.3 结构配方图像 生物信息 纯度 ≥98% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Regulatory Review
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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