merck millipore,默克密理愽
  • merck millipore,默克密理博,420600,Ketoconazole - CAS 65277-42-1 - Calbiochem

  • merck millipore,默克密理博,420600,Ketoconazole - CAS 65277-42-1 - Calbiochem

    产品名称：Ketoconazole - CAS 65277-42-1 - Calbiochem
    产品型号：420600
    An inhibitor of cytochrome P-450 in steroid biosynthesis. An antifungal agent that displays potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities.

    merck millipore,默克密理博,420600,Ketoconazole - CAS 65277-42-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,420600,Ketoconazole - CAS 65277-42-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₆H₂₈Cl₂N₄O₄65277-42-1
    描述
    概述 An inhibitor of cytochrome P-450 in steroid biosynthesis. An antifungal agent that displays potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities. Also acts as an inhibitor of 5-lipoxygenase (5-LO; IC50 = 26 µM) and thromboxane synthase activities.
    产品目录编号 420600
    品牌系列 Calbiochem®
    同义词 cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine, R-41400, CYP17A1 Inhibitor I
    参考
    参考 van Wauwe, J.P., and Janssen, P.A.J. 1989. J. Med. Chem. 32, 2231.
    Beetens, J.R., et al. 1986. Biochem. Pharmacol. 35, 883.
    Lambert, A., et al. 1986. Biochem. Pharmacol. 35, 3999.
    Tucker, W.F.G., and MacNeil, S. 1986. Br. Med. J. 293, 882.
    Lelcuk, S., et al. 1984. J. Trauma 24, 393.
    产品信息
    CAS号 65277-42-1
    形式 Off-white solid
    Hill配方 C₂₆H₂₈Cl₂N₄O₄
    化学配方 C₂₆H₂₈Cl₂N₄O₄
    Molar Mass 531.4
    结构配方图像
    生物信息
    主靶 5-LO
    主靶IC50 26 µM
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO
    GHS安全信息
    RTECS TK7912300
    安全信息
    R相 R: 25-40-63-36/37/38

    Toxic if swallowed.
    Limited evidence of a carcinogenic effect.
    Possible risk of harm to the unborn child.
    Irritating to eyes, respiratory system and skin.
    S相 S: 22-26-36

    Do not breathe dust.
    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Toxic & Carcinogenic / Teratogenic
    有害材料注意事项： Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
    储存 +2°C to +8°C
    无需冷冻 No

    merck millipore,默克密理博,420600,Ketoconazole - CAS 65277-42-1 - Calbiochem

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