merck millipore,默克密理愽
  • merck millipore,默克密理博,420220,iPSC Induction Enhancer, Thiazovivin - Calbiochem

  • merck millipore,默克密理博,420220,iPSC Induction Enhancer, Thiazovivin - Calbiochem

    产品名称：iPSC Induction Enhancer, Thiazovivin - Calbiochem
    产品型号：420220
    A cell-permeable aminothiazolo-carboxamide compound that is reported to augment SB431542 and PD0325901.

    merck millipore,默克密理博,420220,iPSC Induction Enhancer, Thiazovivin - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,420220,iPSC Induction Enhancer, Thiazovivin - Calbiochem

    重要规格表

    经验配方
    C₁₅H₁₃N₅OS
    描述
    概述 A cell-permeable aminothiazolo-carboxamide compound that is ~5-fold more potent than Y-27632 (Cat. Nos. 688000 & 688001) as a ROCK inhibitor (71% inhibition at 2 µM). Effectively prevents trypsinization-induced apoptosis in hESC cultures by stabilizing newly synthesized cell surface E-cadherin and cell-cell adhesion. Unlike, Ptn (Cat. No. 544049), Tzv protects dissociated hESCs even in the absence of ECM. Greatly augments SB431542 (Cat. No. 616461) and PD0325901 (Cat. No. 444966) in improving iPSCs generation efficiency from 4-TF- (Oct44, Klf4, Sox2, and c-Myc) transfected fibroblast cultures.
    产品目录编号 420220
    品牌系列 Calbiochem®
    同义词 N-Benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide, Induced Pluripotent Stem Cells Induction Enhancer, Rho Kinase Inhibitor XII
    参考
    参考 Xu, Y., et al. 2010. Proc. Natl. Acad. Sci. USA 107, 8129
    Lin, T., et al. 2009. Nat. Methods 6, 805.
    产品信息
    形式 Tan powder
    Hill配方 C₁₅H₁₃N₅OS
    化学配方 C₁₅H₁₃N₅OS
    Molar Mass 311.4
    结构配方图像
    生物信息
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,420220,iPSC Induction Enhancer, Thiazovivin - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,385931,Hyaluronidase, Bovine Testes
下一件merck millipore产品：merck millipore,默克密理博,612084,TIMP-2, Human Rheumatoid Synovial Fibroblast - Calbiochem


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