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描述 概述 Recombinant, human interleukin-13 expressed in E. coli. Pleiotropic cytokine that shares many of the properties of IL-4. Exhibits IL-4-like activities on monocytes/macrophages and human B cells but has no effect on T cells. A potent regulator of STAT6 and JAK3 in NK and T cells. Regulates inflammatory and immune responses. Inhibits inducible nitric oxide synthase in human mesangial cells. 产品目录编号 407715 品牌系列 Calbiochem®
同义词 rhIL-13 参考 参考 Yu, C.R., et al. 1998. J. Immunol. 161, 218.
Saura, M., et al. 1996. Biochem. J. 313, 641.
Xi, X., et al. 1995. Br. J. Haematol. 90, 921.
Zurawski, G., and DeVries, J.E. 1994. Stem Cells 12, 169.
McKenzie, A.N.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 3735.
Minty, A., et al. 1993. Nature 362, 248.产品信息 CAS号 148157-34-0 形式 Lyophilized 配方 Lyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-13. Molar Mass 12000 生物信息 生物活性 ED₅₀ = 3.0-6.0 ng/ml as measured in a cell proliferation assay using a human factor-dependent cell line, TF-1 纯度 ≥97% by SDS-PAGE 理化信息 污染物 Endotoxin: <100 pg/µg IL-13 溶解度 Sterile PBS containing ≥0.1% HSA or BSA 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 ≤ -70°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
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