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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS602 Replaces MABT466 描述 Anti-CCT4 Antibody Alternate Names - CCT4
- T-complex protein 1 subunit delta
- TCP-1-delta
- CCT-delta
- Stimulator of TAR RNA-binding
背景信息 The protein named T-complex protein 1 subunit delta or TCP-1-delta, or CCT-delta, or Stimulator of TAR RNA-binding and encoded by the human gene named CCT4/CCTD/SRB is a protein that acts as a molecular chaperone for various proteins during folding. CCT4 is part of the TCP1/CCT complex, a large multi-protein complex consisting of two back-to-back rings, each containing 8 unique but homologous subunits that assist in the folding of newly translated polypeptide substrates though multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Among CCT4’s chaperone partners are the important cytoskeletal proteins of actin and tubulin. CCT4 is also part of the BSS/CCT complex that is a large complex of chaperone like proteins that assist in ciliogenesis and vesicle transport. CCT4 is localized in the cytoplasm and in complex with cytoskeletal elements and centrosomes during cytokinesis. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Anti-CCT4 Antibody is a highly specific rabbit polyclonal antibody, that targets T-complex protein 1 subunit delta & has been tested in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected CCT4 in human liver cancer tissue. 生物信息 免疫原品种 GST-tagged fusion protein corresponding to human CCT4. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - SRB
- CCT4
- CCTD
纯化方法 Antigen Affinity purified UniProt编号 - P50991
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa cell lysate.
Western Blotting Analysis: A 1:500 dilution of this antibody detected CCT4 in HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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