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描述 概述 Recombinant, human soluble interleukin-6 receptor expressed in S. frugiperda insect cells. Soluble form of the IL-6 receptor that binds IL-6 and mediates IL-6 signaling through interaction with gp130. Elevated serum levels of soluble IL-6 receptors have been shown to be associated with a number of pathological states including multiple myelomas, adult T cell leukemia, interstitial lung infection, and HIV infection. 产品目录编号 407653 品牌系列 Calbiochem®
同义词 rhIL-6 sR 参考 参考 Schobitz, B., et al. 1995. FASEB J. 9, 659.
Yokoyama, A., et al. 1995. Clin. Exp. Immunol. 100, 325.
Suzuki, H., et al. 1993. Eur. J. Immunol. 23, 1078.
Lust, J.A., et al. 1992. Cytokine 4, 96.
Sugita, T., et al. 1990. J. Exp. Med. 171, 2001.
Yamasaki, K., et al. 1988. Science 241, 825.产品信息 形式 Lyophilized 配方 Lyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-6 receptor. Molar Mass 38000 生物信息 生物活性 ED₅₀= ≥5 ng/ml as measured by its ability to enhance IL-6-induced growth inhibition of mouse M1 myeloid leukemic cells 纯度 ≥97% by SDS-PAGE 理化信息 污染物 Endotoxin: ≤1 EU/µg 溶解度 Sterile PBS containing ≥0.1% HSA or BSA 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 ≤ -70°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
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