merck millipore,默克密理愽
  • merck millipore,默克密理博,401491,IKK Inhibitor XII - CAS 928655-63-4 - Calbiochem

  • merck millipore,默克密理博,401491,IKK Inhibitor XII - CAS 928655-63-4 - Calbiochem

    产品名称：IKK Inhibitor XII - CAS 928655-63-4 - Calbiochem
    产品型号：401491
    The IKK Inhibitor XII, also referenced under CAS 928655-63-4, controls the biological activity of IKK. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.

    merck millipore,默克密理博,401491,IKK Inhibitor XII - CAS 928655-63-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,401491,IKK Inhibitor XII - CAS 928655-63-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₉H₁₆ClN₃O₃S928655-63-4
    描述
    概述 A cell-permeable amino-diarylbenzamide compound that acts as a potent ATP site-targeting inhibitor against IKK-1 and IKK-2 (pIC50 = 6.4 and 7.0, respectively), while exhibiting more than 50-fold less potency toward a panel of greater than 50 other kinases, including IKK-3 (pIC50 <4.8), ALK5, Cdk-2, EGFR, ErbB2, GSK-3β, Plk1, Src, and VEGFR-2. Shown to effectively suppress LPS-stimulated secretion of TNF-α, IL-1β, and IL-6 from human PBMCs (pIC50 = 6.1, 6.4, and 5.7, respectively) as well as TNF-α-induced NF-κB nuclear translocation in human lung fibroblast cells (pIC50 = 5.7).
    产品目录编号 401491
    品牌系列 Calbiochem®
    参考
    参考 Christopher, J.A., et al. 2007. Bioorg. Med. Chem. Lett. 17, 3972.
    产品信息
    CAS号 928655-63-4
    形式 Off-white solid
    Hill配方 C₁₉H₁₆ClN₃O₃S
    化学配方 C₁₉H₁₆ClN₃O₃S
    Molar Mass 401.9
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,401491,IKK Inhibitor XII - CAS 928655-63-4 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,ES001-1L-K,TMB/E Single Reagent, Blue color, Horseradish Peroxidase Substrate (soluble)


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