merck millipore,默克密理愽
  • merck millipore,默克密理博,401006,Hypoestoxide, Hypoestes rosea - Calbiochem

  • merck millipore,默克密理博,401006,Hypoestoxide, Hypoestes rosea - Calbiochem

    产品名称：Hypoestoxide, Hypoestes rosea - Calbiochem
    产品型号：401006
    A naturally occurring, cell-permeable diterpene with anti-inflammatory properties.

    merck millipore,默克密理博,401006,Hypoestoxide, Hypoestes rosea - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,401006,Hypoestoxide, Hypoestes rosea - Calbiochem

    重要规格表

    经验配方
    C₂₂H₃₂O₅
    描述
    概述 A naturally occurring, cell-permeable diterpene with anti-inflammatory properties. Acts as a selective and direct inhibitor of IκB kinase (IC50 = 24 µM) in TNF-α stimulated HeLa cells, thereby preventing NF-κB activation. Also inhibits the production of nitric oxide by IL-1β or IL-17 stimulated normal human chondrocytes. Reported to neither affect the synthesis of prostaglandin nor inhibit the activities of JNK and p38MAPK.
    产品目录编号 401006
    品牌系列 Calbiochem®
    参考
    参考 Pulai, J.I., et al. 2005. J. Immunol. 174, 5781.
    Ojo-Amaize, E. A., et al. 2002. Cancer Res. 62, 4007.
    Ojo-Amaize, E.A., et al. 2001. Cell Immunol. 209, 149.
    产品信息
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₂H₃₂O₅
    化学配方 C₂₂H₃₂O₅
    Molar Mass 376.5
    可逆 N
    结构配方图像
    生物信息
    主靶 IKB Kinase
    主靶IC50 24 µM against IκB kinase
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    安全信息
    R相 R: 20/21/22

    Harmful by inhalation, in contact with skin and if swallowed.
    S相 S: 36

    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions in DMSO are stable for up to 2 weeks at -20°C. Stock solutions in ethanol are stable for up to 2 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,401006,Hypoestoxide, Hypoestes rosea - Calbiochem

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