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merck millipore,默克密理博,400600,L-N⁵-(1-Iminoethyl)ornithine, Dihydrochloride - CAS 159190-44-0 - Calbiochem
产品名称:L-N⁵-(1-Iminoethyl)ornithine, Dihydrochloride - CAS 159190-44-0 - Calbiochem
产品型号:400600
A cell-permeable, more potent inhibitor of endothelial nitric oxide synthase compared to other arginine analogs such as L-NAME and L-NMMA.
merck millipore,默克密理博,400600,L-N⁵-(1-Iminoethyl)ornithine, Dihydrochloride - CAS 159190-44-0 - Calbiochem
- 产品介绍
- merck millipore,默克密理博,400600,L-N⁵-(1-Iminoethyl)ornithine, Dihydrochloride - CAS 159190-44-0 - Calbiochem
重要规格表
经验配方 CAS号 C₇H₁₅N₃O₂ · 2HCl 159190-44-0 描述 概述 A cell-permeable, more potent inhibitor of endothelial nitric oxide synthase (eNOS; IC50 = 500 nM) compared to other arginine analogs such as L-NAME (Cat. No. 483125) and L-NMMA (Cat. No. 475886). Inhibits acetylcholine-induced relaxation of rat aorta rings (IC50 = 2 µM) and causes a dose-dependent increase in mean arterial blood pressure in the rat (EC50 = 19.5 mg/kg). 产品目录编号 400600 品牌系列 Calbiochem®
同义词 L-NIO, 2HCl 参考 参考 Moore, W.M., et al. 1994. J. Med. Chem. 37, 3886.
Rees, D.D., et al. 1990. Br. J. Pharmacol. 101, 746.产品信息 CAS号 159190-44-0 具有ATP竞争性 N 形式 White solid Hill配方 C₇H₁₅N₃O₂ · 2HCl 化学配方 C₇H₁₅N₃O₂ · 2HCl Molar Mass 246.1 吸湿 Hygroscopic
可逆 N 结构配方图像 生物信息 主靶 eNOS 主靶IC50 500 nM against endothelial nitric oxide synthase (eNOS); 2 µM against acetylcholine-induced relaxation of rat aorta rings; EC50 = 19.5 mg/kg for a dose-dependent increase in mean arterial blood pressure in the rat 纯度 ≥98% by TLC 理化信息 细胞可渗透 Y 溶解度 H₂O 安全信息 R相 R: 36/37/38
Irritating to eyes, respiratory system and skin.S相 S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Irritant
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
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