• merck millipore,默克密理博,400600,L-N⁵-(1-Iminoethyl)ornithine, Dihydrochloride - CAS 159190-44-0 - Calbiochem
  • merck millipore,默克密理博,400600,L-N⁵-(1-Iminoethyl)ornithine, Dihydrochloride - CAS 159190-44-0 - Calbiochem

    产品名称:L-N⁵-(1-Iminoethyl)ornithine, Dihydrochloride - CAS 159190-44-0 - Calbiochem
    产品型号:400600
    A cell-permeable, more potent inhibitor of endothelial nitric oxide synthase compared to other arginine analogs such as L-NAME and L-NMMA.

    merck millipore,默克密理博,400600,L-N⁵-(1-Iminoethyl)ornithine, Dihydrochloride - CAS 159190-44-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,400600,L-N⁵-(1-Iminoethyl)ornithine, Dihydrochloride - CAS 159190-44-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₇H₁₅N₃O₂ · 2HCl159190-44-0
    描述
    概述 A cell-permeable, more potent inhibitor of endothelial nitric oxide synthase (eNOS; IC50 = 500 nM) compared to other arginine analogs such as L-NAME (Cat. No. 483125) and L-NMMA (Cat. No. 475886). Inhibits acetylcholine-induced relaxation of rat aorta rings (IC50 = 2 µM) and causes a dose-dependent increase in mean arterial blood pressure in the rat (EC50 = 19.5 mg/kg).
    产品目录编号 400600
    品牌系列 Calbiochem®
    同义词 L-NIO, 2HCl
    参考
    参考 Moore, W.M., et al. 1994. J. Med. Chem. 37, 3886.
    Rees, D.D., et al. 1990. Br. J. Pharmacol. 101, 746.
    产品信息
    CAS号 159190-44-0
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₇H₁₅N₃O₂ · 2HCl
    化学配方 C₇H₁₅N₃O₂ · 2HCl
    Molar Mass 246.1
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 eNOS
    主靶IC50 500 nM against endothelial nitric oxide synthase (eNOS); 2 µM against acetylcholine-induced relaxation of rat aorta rings; EC50 = 19.5 mg/kg for a dose-dependent increase in mean arterial blood pressure in the rat
    纯度 ≥98% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 H₂O
    安全信息
    R相 R: 36/37/38

    Irritating to eyes, respiratory system and skin.
    S相 S: 26-36

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

    merck millipore,默克密理博,400600,L-N⁵-(1-Iminoethyl)ornithine, Dihydrochloride - CAS 159190-44-0 - Calbiochem

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