merck millipore,默克密理愽
  • merck millipore,默克密理博,400010,Caspase-1 Inhibitor I - CAS 143313-51-3 - Calbiochem

  • merck millipore,默克密理博,400010,Caspase-1 Inhibitor I - CAS 143313-51-3 - Calbiochem

    产品名称：Caspase-1 Inhibitor I - CAS 143313-51-3 - Calbiochem
    产品型号：400010
    The Caspase-1 Inhibitor I, also referenced under CAS 143313-51-3, controls the biological activity of Caspase-1. This small molecule/inhibitor is primarily used for Cancer applications.

    merck millipore,默克密理博,400010,Caspase-1 Inhibitor I - CAS 143313-51-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,400010,Caspase-1 Inhibitor I - CAS 143313-51-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₃H₃₂N₄O₈143313-51-3
    描述
    概述 A potent, specific, and reversible inhibitor of caspase-1 (Ki = 200 pM for human recombinant caspase-1), caspase-4, and caspase-5. Strongly inhibits anti-APO-1 induced apoptosis in L929-APO-1 cells.
    产品目录编号 400010
    品牌系列 Calbiochem®
    同义词 IL-1β Converting Enzyme (ICE) Inhibitor I, Ac-YVAD-CHO, L-709049
    参考
    参考 Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
    Hilbi, H., et al. 1998. J. Biol. Chem. 273, 32895.
    Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
    Los, M., et al. 1995. Nature 375, 81.
    Walker, N.P.C., et al. 1994. Cell 78, 343.
    Wilson, K.P., et al. 1994. Nature 370, 270.
    Thornberry, N.A., et al. 1992. Nature 356, 768.
    产品信息
    CAS号 143313-51-3
    具有ATP竞争性 N
    形式 White powder
    Hill配方 C₂₃H₃₂N₄O₈
    化学配方 C₂₃H₃₂N₄O₈
    Molar Mass 492.5
    肽序列 Ac-Tyr-Val-Ala-Asp-CHO
    可逆 Y
    结构配方图像
    生物信息
    主靶 caspase-1, human recombinant
    主靶Ki 200 pM for human recombinant caspase-1
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO or H₂O
    肽序列 Ac-Tyr-Val-Ala-Asp-CHO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

    merck millipore,默克密理博,400010,Caspase-1 Inhibitor I - CAS 143313-51-3 - Calbiochem

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